Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240104 | 0.86 | MMP9 (0.56) | MMP9MMP1 | |
| SCHEMBL5559059 | 0.84 | MMP9 (0.51) | MMP9MMP1OPRM1OPRK1OPRL1 | |
| SCHEMBL3236312 | 0.82 | MMP9 (0.58) | MMP9MMP1OPRL1 | |
| SCHEMBL3240190 | 0.77 | MMP9 (0.65) | MMP9MMP1OPRL1 | |
| SCHEMBL3233136 | 0.76 | MMP9 (0.51) | MMP9MMP1 | |
| SCHEMBL3237638 | 0.76 | CTNNB1 (0.54) | MMP9MMP1 | |
| SCHEMBL3241861 | 0.75 | CTNNB1 (0.55) | MMP9MMP1 | |
| SCHEMBL3238075 | 0.74 | MMP9 (0.56) | MMP9MMP1 | |
| SCHEMBL5553600 | 0.73 | MMP9 (0.70) | MMP9MMP1OPRL1 | |
| SCHEMBL8359448 | 0.73 | MMP9 (0.73) | MMP9MMP1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |