Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23460193 | 0.77 | L3MBTL1 (0.45) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL18004666 | 0.71 | MAPT (0.51) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL7067985 | 0.70 | MAPT (0.74) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL10408657 | 0.69 | PDE10A (0.55) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13310492 | 0.69 | MAPT (0.55) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL18189826 | 0.68 | MEN1 (0.42) | KMT2AMEN1POLBGPR55MAPT | |
| SCHEMBL8822991 | 0.68 | KMT2A (0.66) | KMT2AMEN1POLBGPR55MAPT | |
| SCHEMBL5391337 | 0.67 | MAPT (0.49) | KMT2AMEN1POLBGPR55MAPT | |
| SCHEMBL14557189 | 0.67 | AURKA (0.43) | KMT2AMEN1POLBGPR55MAPT | |
| SCHEMBL9738364 | 0.65 | MEN1 (0.61) | KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569248-B1 | GIP INHIBITORS FOR IMPROVING COGNITIVE FUNCTION | KAO CORP (JP) | 2023-12-06 | — | — | EP | claimed |
| EP-3560515-B1 | GIP INHIBITORS FOR USE IN IMPROVING MOTOR CONTROL FUNCTION | KAO CORP (JP) | 2023-11-15 | — | — | EP | claimed |
| EP-3569248-A1 | COGNITIVE FUNCTION IMPROVING AGENT | Kao Corporation (JP) | 2019-11-20 | — | — | EP | claimed |
| US-20190330333-A1 | Cognitive Function Improving Agent | KAO CORPORATION (JP) | 2019-10-31 | — | — | US | claimed |
| US-20190330332-A1 | Hypothermia Ameliorating Agent | KAO CORPORATION (JP) | 2019-10-31 | — | — | US | claimed |
| US-20190330334-A1 | Motor Control Function Improving Agent | KAO CORPORATION (JP) | 2019-10-31 | — | — | US | claimed |
| EP-3560515-A1 | MOTOR CONTROL FUNCTION IMPROVING AGENT | Kao Corporation (JP) | 2019-10-30 | — | — | EP | claimed |
| EP-3560514-A1 | HYPOTHERMIA AMELIORATING AGENT | Kao Corporation (JP) | 2019-10-30 | — | — | EP | claimed |
| EP-3569248-B1 | GIP INHIBITORS FOR IMPROVING COGNITIVE FUNCTION | KAO CORP (JP) | 2023-12-06 | — | — | EP | disclosed |
| EP-3560515-B1 | GIP INHIBITORS FOR USE IN IMPROVING MOTOR CONTROL FUNCTION | KAO CORP (JP) | 2023-11-15 | — | — | EP | disclosed |
| US-11555069-B2 | Cognitive function improving agent | KAO CORPORATION (JP) | 2023-01-17 | — | — | US | disclosed |
| US-11319369-B2 | Motor control function improving agent | KAO CORPORATION (JP) | 2022-05-03 | — | — | US | disclosed |
| US-20210212959-A1 | GIP ELEVATION INHIBITOR | KAO CORPORATION (JP) | 2021-07-15 | — | — | US | disclosed |
| EP-3797763-A1 | GIP ELEVATION INHIBITOR | Kao Corporation (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-2011492-A1 | GIP SECRETION INHIBITOR | KAO CORPORATION (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-7081473-B2 | Agent for preventing/ameliorating obesity comprising methylidene hydrizide compound as active ingredient | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-07-25 | — | — | US | disclosed |
| US-20050159415-A1 | Agents for preventing or ameliorating insulin resistance and /or obesity | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2005-07-21 | — | — | US | disclosed |
| EP-1506777-A1 | OBESITY PREVENTIVE OR AMELIORATOR CONTAINING METHYLIDENE HYDRAZIDE COMPOUND AS ACTIVE INGREDIENT | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-02-16 | — | — | EP | disclosed |
| US-20030157107-A1 | Agents for preventing or ameliorating insulin resistance and/or obesity | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1283058-A1 | AGENTS FOR PREVENTING OR AMELIORATING INSULIN RESISTANCE AND/OR OBESITY | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159415-A1 | Agents for preventing or ameliorating insulin resistance and /or obesity | GIPR, GPR119, GLP1R | KMT2A 4550/4885MEN1 1087/4885POLB 4362/4885 |
| US-20030157107-A1 | Agents for preventing or ameliorating insulin resistance and/or obesity | GIPR, GPR119, GLP1R | KMT2A 4124/4885MEN1 1309/4885POLB 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.