Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560850 | 0.87 | CYP1A2 (0.55) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL19695691 | 0.85 | CYP1A2 (0.57) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL6371067 | 0.81 | CYP1A2 (0.55) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL7270296 | 0.81 | CYP1A2 (0.55) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL29604659 | 0.79 | CYP1A2 (0.57) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL9952991 | 0.79 | CYP1A2 (0.57) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL22775583 | 0.79 | CYP1A2 (0.57) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL10680648 | 0.78 | CYP1A2 (0.55) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL7271754 | 0.78 | CYP1A2 (0.55) | CYP1A2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL5286013 | 0.78 | CYP1A2 (0.55) | CYP1A2SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189383-B2 | Radioactively labelled amino acid analogues, their preparation and use | MALLINCKRODT INC. | 2007-03-13 | — | — | US | claimed |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2006-06-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | BCAT1, BCAT2, SLC1A5 | CYP1A2 150/4885SLC7A5 8/4885PTGS1 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.