Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560947 | 0.92 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5396650 | 0.88 | MAPK13 (0.50) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL5400048 | 0.85 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL5401082 | 0.85 | MAPK13 (0.54) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL27666765 | 0.84 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL5392484 | 0.82 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5393306 | 0.82 | MAPK13 (0.61) | MAPK14MAPK13MAPK12MAPK11NPC1 | |
| SCHEMBL5409011 | 0.82 | MAPK13 (0.53) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL5403354 | 0.81 | ALDH1A1 (0.50) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL5560708 | 0.81 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | claimed |