Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380951 | 0.95 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Methylene Chloride SCHEMBL7441159 | 0.88 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL980762 | 0.87 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL16656699 | 0.87 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL978907 | 0.87 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL6157079 | 0.85 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL10933749 | 0.85 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL6160374 | 0.85 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL2226904 | 0.85 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL5354255 | 0.85 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706982-B1 | METHOD OF SEPARATING OPTICAL ISOMERS | DAICEL CHEM (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-6533936-B1 | Efficient, inexpensive resolution using simulated moving bed chromatography having polysaccharide derivative particulate filler | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-03-18 | — | — | US | disclosed |