Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.45 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176568 | 0.95 | YTHDC1 (0.49) | YTHDC1EIF4A3CHRNA7HTR3ACNR1 | |
| SCHEMBL5038866 | 0.95 | YTHDC1 (0.49) | YTHDC1EIF4A3CHRNA7HTR3ACNR1 | |
| Formic Acid SCHEMBL5562495 | 0.91 | CHRNA7 (0.46) | YTHDC1EIF4A3CHRNA7HTR3ANPC1 | |
| Formic Acid SCHEMBL5563457 | 0.87 | DYRK1A (0.52) | — | |
| SCHEMBL1175853 | 0.86 | CHRNA7 (0.49) | YTHDC1EIF4A3CHRNA7HTR3ANPC1 | |
| Formic Acid SCHEMBL5556319 | 0.83 | GSK3B (0.49) | CDK2 | |
| Formic Acid SCHEMBL5562459 | 0.83 | GSK3B (0.41) | FLT3CDK2 | |
| Formic Acid SCHEMBL5562238 | 0.83 | ABL1 (0.37) | EIF4A3USP30 | |
| Formic Acid SCHEMBL5563354 | 0.83 | DYRK1A (0.35) | MAPTRIPK1 | |
| Formic Acid SCHEMBL5556994 | 0.83 | GSK3B (0.39) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |