Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | RAD52 | P43351 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31482686 | 0.98 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| SCHEMBL2860482 | 0.98 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| Bromide SCHEMBL557216 | 0.96 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL30211052 | 0.88 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL326785 | 0.88 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL9358066 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| SCHEMBL29252531 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| Acetic Acid SCHEMBL29252107 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| SCHEMBL29252527 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1POLBKDM4E | |
| SCHEMBL329523 | 0.85 | NPC1 (0.74) | SMN1; SMN2RAB9ANPC1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662478-B1 | ALUMINIUM OR ALUMINIUM ALLOY MOLTEN SALT ELECTROPLATING BATH HAVING GOOD THROWING POWER, AND ELECTROPLATING METHOD AND PRETREATMENT METHOD USING SAME | DIPSOL CHEM (JP) | 2019-08-14 | — | — | EP | disclosed |
| EP-2492376-B1 | METHOD OF BARREL ELECTROPLATING WITH ALUMINUM OR ALUMINUM ALLOY | DIPSOL CHEM (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-10309025-B2 | Aluminum or aluminum alloy molten salt electroplating bath having good throwing power, electroplating method using the bath, and pretreatment method of the bath | DIPSOL CHEMICALS CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-10023968-B2 | Electric Al—Zr alloy plating bath using room temperature molten salt bath and plating method using the same | DIPSOL CHEMICALS CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20180163316-A1 | ALUMINUM OR ALUMINUM ALLOY MOLTEN SALT ELECTROPLATING BATH HAVING GOOD THROWING POWER, ELECTROPLATING METHOD USING THE BATH, AND PRETREATMENT METHOD OF THE BATH | DIPSOL CHEMICALS CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9926638-B2 | Aluminum or aluminum alloy molten salt electroplating bath having good throwing power, electroplating method using the bath, and pretreatment method of the bath | DIPSOL CHEMICALS CO., LTD. (JP) | 2018-03-27 | — | — | US | disclosed |
| US-20170241030-A9 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| CN-103298979-B | The good aluminum or aluminum alloy fuse salt electroplate liquid of distributed force, the electro-plating method being carried out with it and its pre-treating method | 迪普索尔化学株式会社 | 2017-03-08 | — | — | CN | disclosed |
| EP-2130949-B1 | ELECTRIC Al-Zr ALLOY PLATING BATH USING ROOM TEMPERATURE MOLTEN SALT BATH AND PLATING METHOD USING THE SAME | DIPSOL CHEM (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20150159290-A1 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-8916039-B2 | Aluminum or aluminum alloy barrel electroplating method | DIPSOL CHEMICALS CO., LTD. (JP) | 2014-12-23 | — | — | US | disclosed |
| US-8821707-B2 | Electric Al or Al alloy plating bath using room temperature molten salt bath and plating method using the same | DIPSOL CHEMICALS CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| EP-2662478-A1 | ELECTRICAL ALUMINIUM OR ALUMINIUM ALLOY FUSED SALT PLATING BATH HAVING GOOD THROWING POWER, AND ELECTROPLATING METHOD AND PRETREATMENT METHOD USING SAME | Dipsol Chemicals Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-20130292255-A1 | ALUMINUM OR ALUMINUM ALLOY MOLTEN SALT ELECTROPLATING BATH HAVING GOOD THROWING POWER, ELECTROPLATING METHOD USING THE BATH, AND PRETREATMENT METHOD OF THE BATH | DIPSOL CHEMICALS CO., LTD (JP) | 2013-11-07 | — | — | US | disclosed |
| EP-2492376-A1 | METHOD OF BARREL ELECTROPLATING WITH ALUMINUM OR ALUMINUM ALLOY | Dipsol Chemicals Co., Ltd. (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120205249-A1 | Aluminum or Aluminum Alloy Barrel Electroplating Method | HONDA MOTOR CO., LTD. (JP) | 2012-08-16 | — | — | US | disclosed |
| US-20120052324-A1 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120031766-A1 | Electric Al or Al Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | HONDA MOTOR CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20100285322-A1 | Electric Al-Zr Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | DIPSOL CHEMICALS CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2130949-A1 | ELECTRIC Al-Zr ALLOY PLATING BATH USING ROOM TEMPERATURE MOLTEN SALT BATH AND PLATING METHOD USING THE SAME | Dipsol Chemicals Co., Ltd. (JP) | 2009-12-09 | — | — | EP | disclosed |