⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071162 | 0.83 | ALDH1A1 (0.41) | — | |
| SCHEMBL4615113 | 0.79 | CA2 (0.35) | — | |
| SCHEMBL7311317 | 0.77 | — | — | |
| SCHEMBL192919 | 0.77 | — | — | |
| SCHEMBL2427059 | 0.77 | — | — | |
| SCHEMBL7319575 | 0.77 | — | — | |
| SCHEMBL9192338 | 0.77 | — | — | |
| SCHEMBL1982483 | 0.77 | — | — | |
| SCHEMBL7766602 | 0.77 | HIF1A (0.32) | — | |
| SCHEMBL8995181 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7226941-B2 | Compound for treating angiogenesis | HIF BIO, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| EP-1646382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | HIF BIO INC. (US) | 2006-04-19 | — | — | EP | disclosed |
| US-20050187276-A1 | Compounds, compositions and methods | BIZBIOTECH CO., LTD. (KR) | 2005-08-25 | — | — | US | disclosed |
| WO-2005030121-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | HIF BIO, INC. (US) | 2005-04-07 | — | — | WO | disclosed |
| US-4831027-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |
| EP-0263352-A1 | Imidazo-benzoxazinones, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-04-13 | — | — | EP | disclosed |
| US-4361563-A | CARDIOTONIC, ANTITHROMBOTIC | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-11-30 | — | — | US | disclosed |
| EP-0008391-A1 | Benzimidazoles, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1980-03-05 | — | — | EP | disclosed |
| US-4176184-A | CARDIOTONICS, HYPOTENSIVES, ANTITHROMBOTICS AND ANTIARRHYTHMICS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-11-27 | — | — | US | disclosed |