⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869985 | 0.76 | TSHR (0.60) | — | |
| SCHEMBL17272739 | 0.76 | — | — | |
| SCHEMBL17272737 | 0.76 | — | — | |
| SCHEMBL15865299 | 0.74 | — | — | |
| SCHEMBL15865300 | 0.74 | — | — | |
| SCHEMBL15865463 | 0.73 | ADRA2A (0.57) | — | |
| SCHEMBL15865464 | 0.73 | ADRA2A (0.57) | — | |
| SCHEMBL22527576 | 0.73 | MAPT (0.59) | — | |
| SCHEMBL30541932 | 0.73 | MAPT (0.59) | — | |
| SCHEMBL10370721 | 0.72 | MTNR1A (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266896-B1 | Linear or cyclic ureas, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-01-17 | — | — | EP | claimed |
| EP-1266896-B1 | Linear or cyclic ureas, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-01-17 | — | — | EP | disclosed |