Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565253 | 0.72 | NPC1 (0.34) | ALDH1A1TP53SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5568419 | 0.69 | NPY2R (0.42) | SMN1; SMN2KDM4EMAPTL3MBTL1NPC1 | |
| SCHEMBL5563297 | 0.67 | GAA (0.37) | ALDH1A1SMN1; SMN2MAPTHPGDL3MBTL1 | |
| SCHEMBL6454350 | 0.65 | F10 (0.39) | ALDH1A1SMN1; SMN2KDM4EHPGDNPSR1 | |
| SCHEMBL29639818 | 0.63 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL6457868 | 0.61 | F10 (0.68) | ALDH1A1SMN1; SMN2KDM4EHPGDMEN1 | |
| SCHEMBL6454183 | 0.60 | F10 (0.45) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL6454489 | 0.60 | CTSL (0.39) | TP53POLBSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4156611 | 0.58 | ALDH1A1 (0.50) | ALDH1A1POLBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL3429191 | 0.58 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748997-A1 | SUBSTITUTED THIOPHENE-2-CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005111013-A1 | SUBSTITUTED THIOPHENE-2-CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |