SCHEMBL5564889

SCHEMBL5564889

O=C(Nc1ccc(F)cc1-c1ccc(Cl)c(Cl)c1)c1cn(CI)nc1C(F)F

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 18/20 0.47
CHRM2 P08172 7/20 0.44
CHRM1 P11229 7/20 0.44
ALOX15 P16050 1/20 0.38
EIF4E P06730 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4226392 0.91 CHRM3 (0.47) CHRM3CHRM2CHRM1ALOX15
SCHEMBL29349968 0.88 CHRM3 (0.51) CHRM3CHRM2CHRM1ALOX15
SCHEMBL68043 0.88 CHRM3 (0.51) CHRM3CHRM2CHRM1ALOX15
SCHEMBL29445383 0.88 CHRM3 (0.51) CHRM3CHRM2CHRM1ALOX15
SCHEMBL31265248 0.86 CHRM3 (0.51) CHRM3CHRM2CHRM1
SCHEMBL4222835 0.85 CHRM3 (0.47) CHRM3CHRM2CHRM1ALOX15
SCHEMBL14512374 0.84 NPC1 (0.43) CHRM3CHRM2CHRM1ALOX15
SCHEMBL1136276 0.82 CHRM3 (0.51) CHRM3CHRM2CHRM1
SCHEMBL303047 0.82 CHRM3 (0.51) CHRM3CHRM2CHRM1ALOX15
SCHEMBL29688317 0.82 CHRM3 (0.51) CHRM3CHRM2CHRM1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765787-A1 1-ARYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS Merial Limited (US) 2007-03-28 EP disclosed
EP-1761502-A1 N-PHENYLPYRAZOLE DERIVATIVES AS PESTICIDES Merial Limited (US) 2007-03-14 EP disclosed
WO-2006000313-A1 N-PHENYLPYRAZOLE DERIVATIVES AS PESTICIDES MERIAL LTD. (US) 2006-01-05 WO disclosed
WO-2006000311-A1 1-ARYLPYRAZOLE DERIVATIVES PESTICIDAL AGENTS MERIAL LTD. (US) 2006-01-05 WO disclosed