SCHEMBL303047

SCHEMBL303047

Cn1cc(C(=O)Nc2ccc(F)cc2-c2ccc(Cl)c(F)c2)c(C(F)F)n1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 13/20 0.51
CSNK1D P48730 3/20 0.40
CSNK1E P49674 3/20 0.40
WDR5 P61964 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
MAPK1 P28482 1/20 0.39
ALOX15 P16050 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688317 1.00 CHRM3 (0.51) CHRM3CSNK1DCSNK1EWDR5TAS1R3
SCHEMBL29445383 0.93 CHRM3 (0.51) CHRM3ALOX15CHRM2CHRM1
SCHEMBL68043 0.93 CHRM3 (0.51) CHRM3ALOX15CHRM2CHRM1
SCHEMBL29349968 0.93 CHRM3 (0.51) CHRM3ALOX15CHRM2CHRM1
SCHEMBL20986957 0.93 LMNA (0.47) CHRM3WDR5MAPK1
SCHEMBL1136276 0.92 CHRM3 (0.51) CHRM3CHRM2CHRM1
SCHEMBL675989 0.91 CHRM3 (0.49) CHRM3CSNK1DCSNK1ETAS1R3TAS1R1
SCHEMBL29445388 0.91 CHRM3 (0.49) CHRM3CSNK1DCSNK1ETAS1R3TAS1R1
SCHEMBL4222835 0.90 CHRM3 (0.47) CHRM3TAS1R3TAS1R1TAS1R2ALOX15
SCHEMBL19274807 0.89 CHRM3 (0.45) CHRM3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-20160295869-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2016-10-13 US claimed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 WO claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
US-20090118346-A1 Alkyl-Analide Producing Method BAYER CROPSCIENCE AG (DE) 2009-05-07 US claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2009007233-A2 PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES BASF SE (DE) 2009-01-15 WO claimed
EP-1856054-B1 PYRAZOLYLCARBOXANILIDES BAYER CROPSCIENCE AG (DE) 2008-09-17 EP claimed
WO-2008092836-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2008-08-07 WO claimed
EP-1952691-A2 Method for improving plant health by application of a triazolopyrimidine derivative BASF SE (DE) 2008-08-06 EP claimed
EP-1856054-A1 PYRAZOLYLCARBOXANILIDES Bayer CropScience AG (DE) 2007-11-21 EP claimed
WO-2006092213-A1 PYRAZOLYLCARBOXANILIDES BAYER CROPSCIENCE AG (DE) 2006-09-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118346-A1 Alkyl-Analide Producing Method DCXR, MRPL21, APC CHRM3 2870/4885CSNK1D 2625/4885CSNK1E 3045/4885
US-20160295869-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL CHRM3 2676/4885CSNK1D 1228/4885CSNK1E 1891/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC CHRM3 487/4885CSNK1D 3083/4885CSNK1E 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.