Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.64 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.60 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.60 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9969427 | 0.81 | KMT2A (0.57) | S1PR1KMT2AHSD17B10LMNA | |
| SCHEMBL9891039 | 0.81 | S1PR1 (0.69) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL904106 | 0.81 | S1PR1 (0.64) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL17427769 | 0.81 | S1PR1 (0.74) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL9818052 | 0.80 | KMT2A (0.73) | KMT2AHSD17B10LMNA | |
| SCHEMBL27904591 | 0.79 | S1PR1 (0.57) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL8498860 | 0.79 | S1PR1 (0.61) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL566742 | 0.78 | S1PR1 (1.00) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL4245358 | 0.78 | MAPK1 (0.46) | S1PR1TNNC1S1PR3S1PR4SGPL1 | |
| SCHEMBL77965 | 0.78 | KMT2A (0.64) | KMT2AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | SHIVALIK RASAYAN LIMITED (IN) | 2022-05-19 | — | — | US | disclosed |
| EP-1594508-B1 | NOVEL BICYCLIC COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2012-08-08 | — | — | EP | disclosed |
| US-7256206-B2 | 1-[4-(3-Amino-4-hydroxy-3-hydroxymethyl-butyl)-phenyl]-ethanone-O-biphenyl-4-ylmethyl-oxime, used as modulators of lipid activated G-protein coupled receptors specific for sphingosine-1-phosphate; prevention of autoimmune diseases or as angiogenesis inhibitors | IRM LLC (BM) | 2007-08-14 | — | — | US | disclosed |
| US-20040248952-A1 | Novel bicyclic compounds and compositions | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | S1PR2, S1PR4, S1PR5 | S1PR1 6/4885TNNC1 4567/4885S1PR3 4/4885 |
| US-20040248952-A1 | Novel bicyclic compounds and compositions | S1PR1, S1PR3, S1PR5 | S1PR1 1/4885TNNC1 3397/4885S1PR3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.