Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.39 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687901 | 0.84 | TSHR (0.40) | KMT2AHSD17B10S1PR1LMNATNNC1 | |
| SCHEMBL904233 | 0.80 | ALDH1A1 (0.44) | MAPK1KMT2ALMNAMEN1NPC1 | |
| SCHEMBL15190569 | 0.80 | THRA (0.50) | S1PR1TNNC1SGPL1S1PR4GPR183 | |
| SCHEMBL903515 | 0.79 | S1PR1 (0.61) | HSD17B10S1PR1LMNATNNC1SGPL1 | |
| SCHEMBL5565002 | 0.78 | S1PR1 (0.64) | KMT2AHSD17B10S1PR1LMNATNNC1 | |
| SCHEMBL2723135 | 0.78 | TSHR (0.36) | S1PR1LMNATNNC1SGPL1S1PR4 | |
| SCHEMBL29201805 | 0.75 | KMT2A (0.53) | MAPK1KMT2AHSD17B10MAOBLMNA | |
| SCHEMBL9969427 | 0.74 | KMT2A (0.57) | KMT2AHSD17B10MAOBS1PR1LMNA | |
| SCHEMBL9818052 | 0.73 | KMT2A (0.73) | KMT2AHSD17B10MAOBLMNAMMP12 | |
| SCHEMBL4247215 | 0.72 | HSD17B10 (0.57) | MAPK1KMT2AHSD17B10MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056458-A2 | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF FINGOLIMOD | MAPI PHARMA LTD. (IL) | 2012-05-03 | — | — | WO | disclosed |