Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244281 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL15717313 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29244485 | 0.79 | MAPT (0.56) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL5739464 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1RAB9ATDP1 | |
| SCHEMBL6554561 | 0.76 | MAPT (0.64) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL6553599 | 0.76 | MAPT (0.64) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL17974015 | 0.76 | ALDH1A1 (0.64) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL28897034 | 0.76 | ALDH1A1 (0.84) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL6554557 | 0.75 | MAPT (0.62) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL7587537 | 0.74 | FFAR4 (0.53) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765787-A1 | 1-ARYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | Merial Limited (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006000311-A1 | 1-ARYLPYRAZOLE DERIVATIVES PESTICIDAL AGENTS | MERIAL LTD. (US) | 2006-01-05 | — | — | WO | disclosed |