Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617530 | 0.87 | SFRP1 (0.57) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL27935857 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5565189 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL15717313 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL29244485 | 0.83 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6102921 | 0.81 | SFRP1 (0.59) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL17974015 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL28897034 | 0.80 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4617387 | 0.79 | SFRP1 (0.68) | ALDH1A1MAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL4618286 | 0.78 | SFRP1 (0.55) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290334-A | Preparation method of Lifeiste key intermediate | 上海医药工业研究院有限公司 | 2024-07-05 | — | — | CN | disclosed |