SCHEMBL5565210 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.45

▸	MEN1	O00255	1/20	0.45

▸	TSHR	P16473	1/20	0.45

▸	HTT	P42858	1/20	0.45

▸	SMN1; SMN2	Q16637	1/20	0.45

▸	ALDH1A1	P00352	1/20	0.44

▸	MAPK14	Q16539	3/20	0.41

▸	MAPK13	O15264	2/20	0.40

▸	MAPK12	P53778	2/20	0.40

▸	MAPK11	Q15759	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5564738	0.88	F13A1 (0.48)	MAPK14
SCHEMBL5568018	0.86	NPY5R (0.48)	KMT2AMEN1TSHRHTT
SCHEMBL5568908	0.85	F13A1 (0.51)	MAPK14
SCHEMBL5564570	0.85	ALDH1A1 (0.43)	SMN1; SMN2ALDH1A1
SCHEMBL27596142	0.85	MAPK14 (0.40)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5568929	0.85	MAPK14 (0.40)	KMT2AALDH1A1MAPK14MAPK13MAPK12
SCHEMBL5564554	0.85	F13A1 (0.52)	—
SCHEMBL14421713	0.84	NPY5R (0.43)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5564465	0.84	NPY5R (0.51)	KMT2AMEN1TSHRHTT
SCHEMBL5568820	0.84	NPY5R (0.48)	MAPK14MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1480976-B1	THIAZOLE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS	HOFFMANN LA ROCHE (CH)	2007-09-19	—	—	EP	claimed