Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564465 | 0.98 | NPY5R (0.51) | NPY5RTSHRMEN1HTTKMT2A | |
| SCHEMBL5564647 | 0.89 | MAPK13 (0.50) | NPY5RTSHR | |
| SCHEMBL5564570 | 0.86 | ALDH1A1 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL5564738 | 0.86 | F13A1 (0.48) | CYP2C9CYP2C19 | |
| SCHEMBL5565210 | 0.86 | KMT2A (0.45) | TSHRMEN1HTTKMT2A | |
| SCHEMBL27614917 | 0.85 | F2 (0.37) | — | |
| SCHEMBL14421713 | 0.85 | NPY5R (0.43) | NPY5RCYP2C9CYP2C19 | |
| SCHEMBL7151520 | 0.85 | ALDH1A1 (0.47) | — | |
| SCHEMBL5564038 | 0.84 | MAPT (0.43) | TSHRMEN1HTTKMT2A | |
| SCHEMBL5568908 | 0.84 | F13A1 (0.51) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480976-B1 | THIAZOLE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-09-19 | — | — | EP | claimed |