SCHEMBL5565381

SCHEMBL5565381

FC(F)=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1451051 0.97 LMNA (0.35) THRBLMNA
SCHEMBL951360 0.97 LMNA (0.35) THRBLMNA
SCHEMBL1033831 0.97 LMNA (0.35) THRBLMNA
SCHEMBL332706 0.91
SCHEMBL333006 0.78
SCHEMBL333007 0.78
SCHEMBL15798408 0.78
SCHEMBL332988 0.78
SCHEMBL11706402 0.76 THRB (0.32) THRBLMNA
SCHEMBL21802301 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603661-A Fluorinated liquid composition and application thereof 武汉肯达科讯科技有限公司 2024-02-27 CN claimed
CN-114395058-B Binuclear vanadium catalyst and preparation method and application thereof 合肥工业大学 2023-05-12 CN claimed
CN-114984768-A Surface modification method of hollow fiber membrane for artificial membrane lung 上海翊科聚合物科技有限公司 2022-09-02 CN claimed
CN-114395058-A Binuclear vanadium catalyst and preparation method and application thereof 合肥工业大学 2022-04-26 CN claimed
CN-109054578-B Corrosion-resistant epoxy resin powder coating 宁波双人新材料有限公司 2020-11-27 CN claimed
CN-117603661-A Fluorinated liquid composition and application thereof 武汉肯达科讯科技有限公司 2024-02-27 CN disclosed
CN-114395058-B Binuclear vanadium catalyst and preparation method and application thereof 合肥工业大学 2023-05-12 CN disclosed
CN-115305003-A Preparation method and application of super-hydrophobic fingerprint-resistant material 江苏中新瑞光学材料有限公司 2022-11-08 CN disclosed
CN-115073662-A Synthetic method of perfluorinated substituent polyvinyl amine copolymer and application of perfluorinated substituent polyvinyl amine copolymer in perovskite resistive random access memory 郑州大学 2022-09-20 CN disclosed
CN-114984768-A Surface modification method of hollow fiber membrane for artificial membrane lung 上海翊科聚合物科技有限公司 2022-09-02 CN disclosed
CN-114395058-A Binuclear vanadium catalyst and preparation method and application thereof 合肥工业大学 2022-04-26 CN disclosed
CN-113906062-A Polymers and nanoparticles for displacement 沙特阿拉伯石油公司 2022-01-07 CN disclosed
US-5959056-A FUSER ROLL COATED WITH HEAT RESISTANT POLYDIORGANOSILOXANE RELEASE AGENT LEXMARK INTERNATIONAL, INC. (US) 1999-09-28 US disclosed
US-5952442-A COMPRISING SILICONE COPOLYMER; ELECTROPHOTOGRAPHY; LEAKPROOFING LEXMARK INTERNATIONAL, INC. (US) 1999-09-14 US disclosed
US-5929186-A Method for making silicone copolymers LEXMARK INTERNATIONAL, INC. (US) 1999-07-27 US disclosed
US-5880244-A Sealant materials for toner cartridges LEXMARK INTERNATIONAL, INC. (US) 1999-03-09 US disclosed
EP-0878500-A1 Polyorganisiloxane release for agent for use in the fuser system in an electrophotographic process Lexmark International, Inc. (US) 1998-11-18 EP disclosed
EP-0878499-A1 Sealant materials for toner cartridges Lexmark International, Inc. (US) 1998-11-18 EP disclosed
EP-0878498-A1 Method for making silicone copolymers Lexmark International, Inc. (US) 1998-11-18 EP disclosed
US-5783719-A CATALYTIC REACTION OF AN ALKENE WITH A METHYLHYDROGENSILOXANE; MOLECULAR WEIGHT CONTROL LEXMARK INTERNATIONAL, INC. (US) 1998-07-21 US disclosed