Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380710 | 0.88 | AKR1C3 (0.50) | AKR1C3GAAMAPTPOLBBCL2 | |
| SCHEMBL8229598 | 0.80 | POLB (0.44) | MAPTPOLBMCL1ALDH1A1KMT2A | |
| SCHEMBL8578095 | 0.78 | AKR1C3 (0.55) | AKR1C3GAAMAPTPOLBALDH1A1 | |
| SCHEMBL9625706 | 0.77 | AKR1C3 (0.59) | AKR1C3GAAMAPTPOLBALDH1A1 | |
| SCHEMBL8376800 | 0.77 | POLB (0.65) | AKR1C3GAAMAPTPOLBALDH1A1 | |
| SCHEMBL10585003 | 0.77 | AKR1C3 (0.50) | AKR1C3GAAMAPTPOLBALDH1A1 | |
| SCHEMBL10523721 | 0.76 | ALDH1A1 (0.46) | AKR1C3GAAMAPTBCL2MCL1 | |
| SCHEMBL28826038 | 0.76 | MAPT (0.59) | AKR1C3GAAMAPTPOLBALDH1A1 | |
| SCHEMBL28425419 | 0.74 | RAB9A (0.45) | AKR1C3GAAMAPTPOLBBCL2 | |
| SCHEMBL28423660 | 0.74 | RAB9A (0.51) | AKR1C3GAAMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070128441-A1 | Process for the production of strongly adherent coatings | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-07 | — | — | US | disclosed |