Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117439 | 0.84 | BLM (0.61) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL10778604 | 0.84 | BLM (0.61) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL3117431 | 0.84 | BLM (0.61) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL10935109 | 0.82 | BLM (0.64) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL4245716 | 0.82 | BLM (0.59) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL4245719 | 0.82 | BLM (0.59) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL5329866 | 0.82 | BLM (0.64) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL22074782 | 0.82 | BLM (0.59) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL22033172 | 0.82 | BLM (0.59) | BLMSMN1; SMN2HIF1AESR1CA2 | |
| SCHEMBL5329860 | 0.82 | BLM (0.64) | BLMSMN1; SMN2HIF1AESR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100581589-C | Radiolabeled amino acid analogs, their preparation and use | MALLINCKRODT INC | 2010-01-20 | — | — | CN | disclosed |
| US-20070081941-A1 | F-18 Labeled Amino Acid Analogs | MALLINCKRODT INC. (US) | 2007-04-12 | — | — | US | disclosed |
| US-7189383-B2 | Radioactively labelled amino acid analogues, their preparation and use | MALLINCKRODT INC. | 2007-03-13 | — | — | US | disclosed |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2006-06-15 | — | — | US | disclosed |
| CN-1674943-A | Radiolabeled amino acid analogs, their preparation and use | MALLINCKRODT INC (US) | 2005-09-28 | — | — | CN | disclosed |
| EP-1539250-A1 | RADIOACTIVELY LABELLED AMINO ACID ANALOGUES, THEIR PREPARATION AND USE | Mallinckrodt Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004110500-A1 | RADIOACTIVELY LABELLED AMINO ACID ANALOGUES, THEIR PREPARATION AND USE | MALLINCKRODT INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070081941-A1 | F-18 Labeled Amino Acid Analogs | BCAT1, BCAT2, SLC1A5 | BLM 4365/4885SMN1; SMN2 3049/4885HIF1A 699/4885 |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | BCAT1, BCAT2, SLC1A5 | BLM 4261/4885SMN1; SMN2 3851/4885HIF1A 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.