Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.74 |
| ▸ | CTSK | P43235 | 11/20 | 0.74 |
| ▸ | CTSB | P07858 | 4/20 | 0.74 |
| ▸ | CTSL | P07711 | 2/20 | 0.74 |
| ▸ | AKT1 | P31749 | 1/20 | 0.71 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969908 | 1.00 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL21010315 | 0.94 | CTSS (0.79) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2440946 | 0.94 | CTSS (0.79) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3683727 | 0.91 | REN (0.67) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3686038 | 0.91 | REN (0.67) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2442760 | 0.91 | CTSS (0.76) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2446582 | 0.91 | CTSS (0.76) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL10653885 | 0.91 | CTSS (0.68) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2444606 | 0.90 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2405030 | 0.90 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882452-B1 | METHOD FOR LOWERING THE VISCOSITY OF HIGH-CONCENTRATION PROTEIN SOLUTIONS | ADOCIA (FR) | 2017-04-26 | — | — | EP | disclosed |
| US-9278131-B2 | Process for lowering the viscosity of highly concentrated protein solutions | ADOCIA (FR) | 2016-03-08 | — | — | US | disclosed |
| EP-2882452-A1 | METHOD FOR LOWERING THE VISCOSITY OF HIGH-CONCENTRATION PROTEIN SOLUTIONS | Adocia (FR) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023816-A1 | METHOD FOR LOWERING THE VISCOSITY OF HIGH-CONCENTRATION PROTEIN SOLUTIONS | ADOCIA (FR) | 2014-02-13 | — | — | WO | disclosed |
| US-20140044708-A1 | Process for lowering the viscosity of highly concentrated protein solutions | ADOCIA (FR) | 2014-02-13 | — | — | US | disclosed |
| EP-1973887-B1 | AZA HETEROCYCLICS FOR THE TREATMENT OF MALARIA OR AIDS | IMMUPHARMA FRANCE SA (FR) | 2012-09-19 | — | — | EP | disclosed |
| US-7265096-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1567169-A2 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2005-08-31 | — | — | EP | disclosed |
| US-20040142857-A1 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004041203-A2 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142857-A1 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | TYMP, GDA, GCG | CTSS 1486/4885CTSK 1533/4885CTSB 907/4885 |
| US-20140044708-A1 | Process for lowering the viscosity of highly concentrated protein solutions | F13B, F5, F12 | CTSS 3645/4885CTSK 2680/4885CTSB 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.