SCHEMBL5566136

SCHEMBL5566136

CC(=CC(=C(C=C(C)C(=O)O)c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.54
CYP2C9 P11712 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
PARP1 P09874 1/20 0.46
PARP15 Q460N3 1/20 0.46
PARP10 Q53GL7 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NFE2L2 Q16236 1/20 0.45
HTT P42858 1/20 0.44
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12657652 0.91 AKR1C3 (0.50) AKR1C3CYP2C9CA12CA1CA2
SCHEMBL2791186 0.84 NFE2L2 (0.59) AKR1C3CYP2C9CA12CA1CA2
SCHEMBL8104632 0.84 NFE2L2 (0.59) AKR1C3CYP2C9CA12CA1CA2
SCHEMBL3386465 0.83 AKR1C3 (0.50) AKR1C3CYP2C9CA12CA1CA2
SCHEMBL28173993 0.79 ELANE (0.45) AKR1C3CYP2C9PARP1PARP15PARP10
SCHEMBL57280 0.78 AKR1C3 (0.46) AKR1C3CYP2C9CA12CA1CA2
SCHEMBL28337501 0.78 AKR1C3 (0.46) AKR1C3CYP2C9CA12CA1CA2
SCHEMBL28097679 0.77 AKR1C3 (0.63) AKR1C3CYP2C9CA12CA1CA2
Biphenyl SCHEMBL21409619 0.76 HTT (0.56) AKR1C3CYP2C9KMT2AHTTALDH1A1
Naphthalene SCHEMBL27557572 0.76 HTT (0.56) AKR1C3CYP2C9KMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070254490-A1 Method of Making a Microelectronic and/or Optoelectronic Circuitry Sheet VERSATILIS, LLC (US) 2007-11-01 US disclosed
US-7259106-B2 Method of making a microelectronic and/or optoelectronic circuitry sheet VERSATILIS LLC (US) 2007-08-21 US disclosed
EP-1803147-A2 METHOD OF MAKING A MICROELECTRONIC AND/OR OPTOELECTRONIC CIRCUITRY SHEET Versatilis LLC (US) 2007-07-04 EP disclosed
US-20070091061-A1 Electrophoretic display device and method for manufacturing such a device KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-04-26 US disclosed
CN-1902531-A Electronic device having a plurality of electro-optical elements KONINKL PHILIPS ELECTRONICS NV (NL) 2007-01-24 CN disclosed
CN-1902532-A Method of producing an electro-optic device and electro-optic device KONINKL PHILIPS ELECTRONICS NV (NL) 2007-01-24 CN disclosed
CN-1806199-A Electrophoretic display device and method of manufacturing the same KONINKL PHILIPS ELECTRONICS NV (NL) 2006-07-19 CN disclosed
US-20060063351-A1 Method of making a microelectronic and/or optoelectronic circuitry sheet VERSATILIS LLC (US) 2006-03-23 US disclosed
EP-1636642-A1 ELECTROPHORETIC DISPLAY DEVICE AND METHOD FOR MANUFACTURING SUCH A DEVICE Koninklijke Philips Electronics N.V. (NL) 2006-03-22 EP disclosed
WO-2006029414-A2 METHOD OF MAKING A MICROELECTRONIC AND/OR OPTOELECTRONIC CIRCUITRY SHEET VERSATILIS LLC (US) 2006-03-16 WO disclosed
WO-2004111716-A1 ELECTROPHORETIC DISPLAY DEVICE AND METHOD FOR MANUFACTURING SUCH A DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-12-23 WO disclosed