Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509683 | 0.88 | ALDH1A1 (0.49) | ALDH1A1ACHEPGRGAAPTGS1 | |
| SCHEMBL10508067 | 0.82 | PTGS2 (0.60) | ALDH1A1PTGS1HSD17B10MAPTPTGS2 | |
| SCHEMBL9325544 | 0.80 | ALDH1A1 (0.60) | ALDH1A1ACHEPGRGAAPTGS1 | |
| SCHEMBL11854401 | 0.78 | ALDH1A1 (0.58) | ALDH1A1ACHEPGRGAAPTGS1 | |
| SCHEMBL11584707 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ACHEPGRGAAPTGS1 | |
| SCHEMBL18026668 | 0.78 | HCRTR1 (0.49) | GAAMAPK1MAPTNPC1 | |
| SCHEMBL11301512 | 0.78 | PTGS2 (0.72) | ALDH1A1ACHEPGRGAAPTGS1 | |
| SCHEMBL8341436 | 0.78 | ALDH1A1 (0.57) | ALDH1A1ACHEPGRGAAPTGS1 | |
| SCHEMBL10347560 | 0.77 | MAPT (0.56) | MAPK1HSD17B10MAPTNPC1MAOB | |
| SCHEMBL30663731 | 0.77 | MAPT (0.56) | MAPK1HSD17B10MAPTNPC1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651034-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2006-05-03 | — | — | EP | claimed |
| WO-2005013687-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | claimed |
| EP-1504664-A1 | Organic compounds | Novartis AG (CH) | 2005-02-09 | — | — | EP | claimed |
| US-8834909-B2 | Granule baits | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | disclosed |
| US-20070071784-A1 | Organic compounds | ELANCO TIERGESUNDHEIT AG (CH) | 2007-03-29 | — | — | US | disclosed |
| EP-1651034-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005013687-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| EP-1504664-A1 | Organic compounds | Novartis AG (CH) | 2005-02-09 | — | — | EP | disclosed |
| US-4205066-A | Bait compositions for anthropophilic flies | AIRWICK INDUSTRIES, INC. (US) | 1980-05-27 | — | — | US | disclosed |
| US-4189475-A | MALTHION AND O,O-DIMETHYL S-(4-AZA-6-CHLORO-2-OXO-BENZOXAZOL-3-YL)-METHYL THIOPHOSPHATE | AIRWICK INDUSTRIES INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4129601-A | BIS ETHERS, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1978-12-12 | — | — | US | disclosed |
| US-4067990-A | SOLUTION OF A PHENYL N-METHYL CARBAMATE | AIRWICK INDUSTRIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |