SCHEMBL5566497

SCHEMBL5566497

CCCCN1C(=O)c2cc(N)c(Br)cc2C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 3/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CASP1 P29466 2/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 3/20 0.39
ATM Q13315 2/20 0.39
MAPK1 P28482 3/20 0.37
USP2 O75604 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
RGS12 O14924 1/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TLR9 Q9NR96 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9155337 0.90 ALDH1A1 (0.36) ALDH1A1HSD17B10MEN1KMT2ACASP1
SCHEMBL28962110 0.88 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AMAPTATM
SCHEMBL22080458 0.88 HSD17B10 (0.44) ALDH1A1HSD17B10MEN1KMT2ACASP1
SCHEMBL9156396 0.83 CYP1B1 (0.45) ALDH1A1HSD17B10MEN1KMT2ACASP1
SCHEMBL28918523 0.78 MEN1 (0.41) ALDH1A1HSD17B10MEN1KMT2ACASP1
SCHEMBL9400279 0.77 APP (0.42) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL3687458 0.76 MAPT (0.36) ALDH1A1MEN1KMT2AMAPTATM
SCHEMBL7519644 0.75 ALDH1A1 (0.63) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL2651666 0.75 HSD17B10 (0.66) ALDH1A1HSD17B10MEN1KMT2ACASP1
SCHEMBL16691732 0.75 CYP1B1 (0.43) ALDH1A1MEN1KMT2AMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981579-B1 COATED CARBON FIBER REINFORCED PLASTIC PARTS BASF SE (DE) 2018-10-17 EP disclosed
US-9410057-B2 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-08-09 US disclosed
US-9410057-B2 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-08-09 US disclosed
US-9410057-B2 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-08-09 US disclosed
CN-105308130-A Coated carbon fiber reinforced plastic part BASF SE 2016-02-03 CN disclosed
US-20160009952-A1 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-01-14 US disclosed
US-20160009952-A1 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-01-14 US disclosed
US-20160009952-A1 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-01-14 US disclosed
US-7169909-B2 Phthalimidylazo dyes, processess for the preparation thereof and the use thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-30 US disclosed
US-20060046596-A1 Phthalimidylazo dyes, processess for the preparation thereof and the use thereof HUNTSMAN INTERNATIONAL LLC 2006-03-02 US disclosed
EP-1572808-A1 PHTHALIMIDYLAZO DYES, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF Ciba SC Holding AG (CH) 2005-09-14 EP disclosed
WO-2004056926-A1 PHTHALIMIDYLAZO DYES, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060046596-A1 Phthalimidylazo dyes, processess for the preparation thereof and the use thereof H1-4, C9, CBR3 ALDH1A1 2701/4885HSD17B10 4015/4885MEN1 1108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.