Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533065 | 0.88 | ACLY (0.42) | ACLYMEN1KMT2AALDH1A1MRGPRX4 | |
| SCHEMBL14228217 | 0.64 | HTR1D (0.44) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29202172 | 0.62 | MRGPRX4 (0.52) | MEN1KMT2AALDH1A1MRGPRX4LMNA | |
| SCHEMBL21931121 | 0.61 | ACLY (1.00) | ACLYMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL21999819 | 0.61 | ACLY (0.64) | ACLYMEN1KMT2AALDH1A1 | |
| SCHEMBL14200016 | 0.58 | GLRA1 (0.43) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL257799 | 0.58 | MAPK1 (0.51) | MEN1KMT2AALDH1A1MRGPRX4LMNA | |
| SCHEMBL6080377 | 0.57 | LMNA (0.47) | MEN1KMT2AALDH1A1MRGPRX4LMNA | |
| SCHEMBL21999821 | 0.57 | ACLY (0.81) | ACLYMEN1KMT2A | |
| SCHEMBL533676 | 0.57 | ACLY (0.46) | ACLYMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610753-A4 | PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC (US) | 2007-07-04 | — | — | EP | disclosed |
| EP-1610753-A2 | PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004073634-A2 | PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC. (US) | 2004-09-02 | — | — | WO | disclosed |