Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681471 | 0.90 | CA2 (0.38) | KDM4ETSHRTDP1CA2CA1 | |
| SCHEMBL202580 | 0.86 | KDM4E (0.38) | KDM4ETSHRTDP1CA2CA1 | |
| SCHEMBL27945649 | 0.83 | KDM4E (0.30) | KDM4ETSHRTDP1 | |
| SCHEMBL6536446 | 0.83 | KDM4E (0.40) | KDM4ETSHRTDP1 | |
| SCHEMBL37506 | 0.83 | KDM4E (0.40) | KDM4ETSHRTDP1 | |
| Sulfuric Acid SCHEMBL21876328 | 0.82 | KDM4E (0.40) | KDM4ETSHRTDP1CA2CA1 | |
| Sulfuric Acid SCHEMBL22118762 | 0.82 | KDM4E (0.40) | KDM4ETSHRTDP1CA2CA1 | |
| SCHEMBL28442614 | 0.80 | KDM4E (0.34) | KDM4ETSHRTDP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL9146130 | 0.80 | KDM4E (0.39) | KDM4ETSHRTDP1CA2CA1 | |
| Iodide SCHEMBL11068952 | 0.80 | KDM4E (0.39) | KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458903-B | Method for producing heteroaromatic sulfonamide compound | 宇部兴产株式会社 | 2021-02-05 | — | — | CN | disclosed |
| US-20070113356-A1 | Reactive polysaccharide derivatives, their preparation and their use | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-24 | — | — | US | disclosed |
| EP-1694713-A1 | REACTIVE POLYSACCHARIDE DERIVATES, THEIR PREPARATION AND THEIR USE | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058975-A1 | REACTIVE POLYSACCHARIDE DERIVATES, THEIR PREPARATION AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-06-30 | — | — | WO | disclosed |
| US-5099025-A | PREPARATION OF 2-CHLORO-5-METHYL-PYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070113356-A1 | Reactive polysaccharide derivatives, their preparation and their use | C1S, H1-0, H1-4 | KDM4E 3249/4885TSHR 4618/4885TDP1 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.