SCHEMBL556671

SCHEMBL556671

Nc1cc(CO)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425493 1.00
SCHEMBL318128 0.83 NOS3 (0.59)
SCHEMBL29857272 0.83
SCHEMBL7169889 0.79 NOS3 (0.55)
SCHEMBL29481458 0.79
SCHEMBL339608 0.79
Hydrochloric Acid SCHEMBL23064166 0.77 NOS3 (0.63)
SCHEMBL12942062 0.77
SCHEMBL2178716 0.77
SCHEMBL19931587 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11028086-B2 Pyrido-imidazo rifamycins BIOFER S.P.A. (IT) 2021-06-08 US claimed
EP-3645539-B1 PYRIDO-IMIDAZO RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT BIOFER SPA (IT) 2021-04-07 EP claimed
US-20200157104-A1 PYRIDO-IMIDAZO RIFAMYCINS BIOFER S.P.A. (IT) 2020-05-21 US claimed
EP-3645539-A1 PYRIDO-IMIDAZO RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT Biofer S.p.A. (IT) 2020-05-06 EP claimed
CN-110770244-A Antibacterial agent of pyridoimidazole rifamycin derivative 倍尔福股份公司 2020-02-07 CN claimed
CN-109134356-A A kind of preparation method of intermediate 2-amino pyridine -4- methanol 苏州盖德精细材料有限公司 2019-01-04 CN claimed
WO-2019003076-A1 PYRIDO-IMIDAZO RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT BIOFER S.P.A. (IT) 2019-01-03 WO claimed
CN-106751439-B A kind of carbinol-modified pnenolic aldehyde foam materials of 2-aminopyridine -4- and preparation method thereof 沈阳化工大学 2018-10-26 CN claimed
CN-106751439-A Carbinol-modified pnenolic aldehyde foam material of a kind of 2 aminopyridine 4 and preparation method thereof 沈阳化工大学 2017-05-31 CN claimed
CN-103664766-A Preparation method of 2-aminopyridine-4-methyl alcohol UNIV ZHEJIANG 2014-03-26 CN claimed
EP-4725941-A1 ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-15 EP disclosed
US-20250361241-A1 HPK1 INHIBITOR AND MEDICAL USE THEREOF BETTA PHARMACEUTICALS CO., LTD. (CN) 2025-11-27 US disclosed
US-RE50663-E1 Heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2025-11-18 US disclosed
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
EP-4626896-A1 POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS Universidad del País Vasco/Euskal Herriko Unibertsitatea (ES) 2025-10-08 EP disclosed
WO-2001017995-A1 TYROSINE KINASE INHIBITORS MERCK & CO., INC. (US) 2001-03-15 WO disclosed
EP-1044967-A2 2-Pyridinylguanidine urokinase inhibitors PFIZER INC. (US) 2000-10-18 EP disclosed
EP-0189678-B1 ELECTROCHEMICAL REDUCTIONS OF PYRIDINE CARBOXAMIDE BASES REILLY INDUSTRIES, INC. (US) 1991-11-06 EP disclosed
US-4695352-A Electrochemical reduction of pyridine carboxamide bases REILLY TAR & CHEMICAL CORPORATION (US) 1987-09-22 US disclosed
EP-0189678-A1 Electrochemical reductions of pyridine carboxamide bases REILLY INDUSTRIES, INC. (US) 1986-08-06 EP disclosed