SCHEMBL318128

SCHEMBL318128

Nc1cc(CCO)ccn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 4/20 0.59
NOS2 P35228 4/20 0.59
NOS1 P29475 3/20 0.59
GABRP O00591 2/20 0.56
GABRD O14764 2/20 0.56
GABRA1 P14867 2/20 0.56
GABRB1 P18505 2/20 0.56
GABRG2 P18507 2/20 0.56
GABRB3 P28472 2/20 0.56
GABRA5 P31644 2/20 0.56
GABRA3 P34903 2/20 0.56
GABRA2 P47869 2/20 0.56
GABRB2 P47870 2/20 0.56
GABRA4 P48169 2/20 0.56
GABRE P78334 2/20 0.56
GABRA6 Q16445 2/20 0.56
GABRG1 Q8N1C3 2/20 0.56
GABRG3 Q99928 2/20 0.56
GABRQ Q9UN88 2/20 0.56
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7169889 0.88 NOS3 (0.55) NOS3NOS2NOS1GABRPGABRD
SCHEMBL29425493 0.83
SCHEMBL556671 0.83
SCHEMBL4134209 0.81 NOS3 (0.61) NOS3NOS2NOS1GABRPGABRD
Hydrochloric Acid SCHEMBL29481452 0.79 NOS3 (0.59) NOS3NOS2NOS1GABRPGABRD
Hydrochloric Acid SCHEMBL6953232 0.79 NOS3 (0.59) NOS3NOS2NOS1GABRPGABRD
SCHEMBL29857272 0.79
SCHEMBL18476749 0.79 NOS3 (0.59) NOS3NOS2NOS1GABRPGABRD
SCHEMBL105611 0.79 NOS2 (0.70) NOS3NOS2NOS1GABRPGABRD
SCHEMBL318127 0.79 NOS3 (0.59) NOS3NOS2NOS1GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585069-A1 PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN Janssen Pharmaceutica, N.V. (BE) 2013-05-01 EP claimed
WO-2012006004-A1 PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN JANSSEN PHARMACEUTICA NV (BE) 2012-01-12 WO claimed
CN-105188887-B Moisture-absorbing material, method for producing same, and packaging material 富士胶片株式会社 2017-07-28 CN disclosed
US-20170015484-A1 MOISTURE-ABSORBING MATERIAL, METHOD FOR PRODUCING SAME, AND BLISTER PACK FUJIFILM CORPORATION (JP) 2017-01-19 US disclosed
US-20160030918-A1 MOISTURE-ABSORBING MATERIAL, METHOD FOR MANUFACTURING SAME, AND PACKAGING MATERIAL FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
CN-105188887-A Moisture-absorbing material, method for producing same, and packaging material FUJIFILM CORP 2015-12-23 CN disclosed
EP-1805038-B1 INK JET RECORDING MEDIUM FUJIFILM CORP (JP) 2013-06-12 EP disclosed
EP-2585069-A1 PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN Janssen Pharmaceutica, N.V. (BE) 2013-05-01 EP disclosed
US-8293343-B2 Inkjet recording medium FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8283005-B2 Inkjet recording medium and method of manufacturing the same FUJIFILM CORPORATION (JP) 2012-10-09 US disclosed
US-8226226-B2 Method for inkjet recording FUJIFILM CORPORATION (JP) 2012-07-24 US disclosed
EP-1805038-A1 INK JET RECORDING MEDIUM Fuji Photo Film Co., Ltd. (JP) 2007-07-11 EP disclosed
WO-2006038666-A1 INK JET RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2006-04-13 WO disclosed
US-20060003113-A1 Ink jet recording medium and method for producing the same FUJI PHOTO FILM CO., LTD. 2006-01-05 US disclosed
EP-1609613-A1 Image recording medium manufacturing method FUJI PHOTO FILM CO., LTD. (JP) 2005-12-28 EP disclosed
US-20050281964-A1 Image recording medium manufacuturing method FUJI PHOTO FILM CO., LTD. 2005-12-22 US disclosed
EP-1595713-A2 Ink jet recording medium and method for producing the same Fuji Photo Film Co., Ltd. (JP) 2005-11-16 EP disclosed
US-20050019506-A1 Ink jet recording medium and method for producing the same FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
EP-1484189-A2 Ink jet recording medium and method for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2004-12-08 EP disclosed
WO-2004022567-A1 HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-18 WO disclosed