Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.30 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.31 |
| ▸ | UGCG | Q16739 | 3/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | AGL | P35573 | 2/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.30 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL23071102 | 1.00 | GLB1 (0.37) | GLB1GBA1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL329125 | 0.97 | GLB1 (0.38) | GLB1GBA1ALDH1A1GAATP53 | |
| Bromide SCHEMBL3800995 | 0.95 | GLB1 (0.34) | GLB1GBA1ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL31332603 | 0.95 | GLB1 (0.37) | GLB1GBA1ALDH1A1GAATP53 | |
| Hydrochloric Acid SCHEMBL558002 | 0.95 | GLB1 (0.37) | GLB1GBA1GAATP53DNM1 | |
| Bromide SCHEMBL28429077 | 0.93 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2D6CYP2C19DNM1 | |
| Bromide SCHEMBL5168952 | 0.93 | GLB1 (0.33) | GLB1 | |
| Bromide SCHEMBL28013294 | 0.93 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2D6CYP2C19DNM1 | |
| SCHEMBL899123 | 0.92 | GLB1 (0.35) | GLB1GBA1GAATP53 | |
| Hydrochloric Acid SCHEMBL29290774 | 0.92 | GLB1 (0.35) | GLB1GBA1ALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112067674-B | Molecularly imprinted electrochemical sensor and folic acid content detection method thereof | 常州市新鸿医药化工技术有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-118380634-A | Rechargeable aluminum battery positive electrode material, rechargeable aluminum battery and preparation method of rechargeable aluminum battery | 南京理工大学 | 2024-07-23 | — | — | CN | claimed |
| CN-112067674-A | Molecular imprinting electrochemical sensor and method for detecting folic acid content by using same | 常州市新鸿医药化工技术有限公司 | 2020-12-11 | — | — | CN | claimed |
| US-8420732-B2 | Polybenzimidazole solution in an ionic liquid | PBI PERFORMANCE PRODUCTS, INC. (US) | 2013-04-16 | — | — | US | claimed |
| WO-2012087442-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. (US) | 2012-06-28 | — | — | WO | claimed |
| US-20120142830-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | DAWKINS BOBBY G (US) | 2012-06-07 | — | — | US | claimed |
| US-20110152413-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. | 2011-06-23 | — | — | US | claimed |
| CN-112067674-B | Molecularly imprinted electrochemical sensor and folic acid content detection method thereof | 常州市新鸿医药化工技术有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118380634-A | Rechargeable aluminum battery positive electrode material, rechargeable aluminum battery and preparation method of rechargeable aluminum battery | 南京理工大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-117143071-A | Preparation method of trans-1, 3-dioxane liquid crystal compound | 宁夏中星显示材料有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-213302075-U | Molecular imprinting electrochemical sensor and device for detecting folic acid content | 常州市新鸿医药化工技术有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112067674-A | Molecular imprinting electrochemical sensor and method for detecting folic acid content by using same | 常州市新鸿医药化工技术有限公司 | 2020-12-11 | — | — | CN | disclosed |
| US-20190291046-A1 | OXYGEN SEPARATION MEMBRANE | SHARP KABUSHIKI KAISHA (JP) | 2019-09-26 | — | — | US | disclosed |
| US-20120142830-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | DAWKINS BOBBY G (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120052324-A1 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120031766-A1 | Electric Al or Al Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | HONDA MOTOR CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20110152413-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. | 2011-06-23 | — | — | US | disclosed |
| CN-101987987-A | Imidazole salt extreme-pressure wear-resistant additive for rape seed oil and preparation method thereof | LANZHOU CHEM PHYS INST | 2011-03-23 | — | — | CN | disclosed |
| US-20100285322-A1 | Electric Al-Zr Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | DIPSOL CHEMICALS CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2130949-A1 | ELECTRIC Al-Zr ALLOY PLATING BATH USING ROOM TEMPERATURE MOLTEN SALT BATH AND PLATING METHOD USING THE SAME | Dipsol Chemicals Co., Ltd. (JP) | 2009-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190291046-A1 | OXYGEN SEPARATION MEMBRANE | NCLN, OXA1L, MB | SIGMAR1 812/4885GLB1 4067/4885GBA1 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.