Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28058257 | 0.97 | CA12 (0.31) | CA5ACA5BCA2CA9CA12 | |
| Sulfuric Acid SCHEMBL28140571 | 0.95 | — | — | |
| Sulfuric Acid SCHEMBL27883581 | 0.95 | — | — | |
| SCHEMBL27844800 | 0.86 | CA2 (0.30) | CA2CA9 | |
| SCHEMBL27323784 | 0.86 | — | — | |
| SCHEMBL20670 | 0.83 | — | — | |
| Sulfuric Acid SCHEMBL28315317 | 0.82 | CA12 (0.34) | CA2CA9CA12CA1CA7 | |
| Sulfuric Acid SCHEMBL27813905 | 0.82 | CA12 (0.34) | CA2CA9CA12CA1CA7 | |
| Bicarbonate SCHEMBL4344138 | 0.81 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL16225173 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7172875-B2 | Identifying inhibitors of intracellular protein fibrillization | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | claimed |
| US-20050153384-A1 | Identifying inhibitors of intracellular protein fibrillization | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-07-14 | — | — | US | claimed |
| WO-2004073651-A2 | IDENTIFYING INHIBITORS OF INTRACELLULAR PROTEIN FIBRILLIZATION | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2004-09-02 | — | — | WO | claimed |
| CN-110418634-A | Oil-in-water type cosmetic for sticking to keratin fiber | JO COSMETICS CO LTD | 2019-11-05 | — | — | CN | disclosed |
| CN-109068628-A | Weeding pesticide composition and the herbicidal methods for using it | 组合化学工业株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-108884091-A | Condensed heterocyclic compouds and noxious organism control agent | 日产化学株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-108885412-A | Processing liquid for semiconductor manufacturing and pattern forming method | 富士胶片株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-108884228-A | The manufacturing method of organopolysilane | 日本曹达株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-104661644-B | Liquid detergent containing sterol ester | 味之素株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-107513308-A | Aqueous ink for inkjet recording, ink jet recording method, ink mist recording thing | 株式会社理光 | 2017-12-26 | — | — | CN | disclosed |
| CN-107427443-A | Solid state powder cosmetic product | 株式会社高丝 | 2017-12-01 | — | — | CN | disclosed |
| CN-107207506-A | Condensed heterocyclic compouds and noxious organism control agent | 日产化学工业株式会社 | 2017-09-26 | — | — | CN | disclosed |
| CN-104185657-B | Resin composition and cosmetic containing the same | 株式会社高丝 | 2017-09-15 | — | — | CN | disclosed |
| CN-106867411-A | For the paste compound, its preparation method, polishing method, the method for manufacture semiconductor devices and the polissoir that chemically-mechanicapolish polish | 三星电子株式会社 | 2017-06-20 | — | — | CN | disclosed |
| CN-104708931-B | Ink jet recording method, ink-jet recording apparatus | 株式会社理光 | 2017-06-16 | — | — | CN | disclosed |
| CN-103370642-B | Colored composition for color filters, and color filter | TOYO INK SC HOLDINGS CO LTD | 2015-07-15 | — | — | CN | disclosed |
| CN-103370642-A | Colored composition for color filters, and color filter | TOYO INK SC HOLDINGS CO LTD | 2013-10-23 | — | — | CN | disclosed |
| US-7172875-B2 | Identifying inhibitors of intracellular protein fibrillization | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20050153384-A1 | Identifying inhibitors of intracellular protein fibrillization | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-07-14 | — | — | US | disclosed |
| WO-2004073651-A2 | IDENTIFYING INHIBITORS OF INTRACELLULAR PROTEIN FIBRILLIZATION | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2004-09-02 | — | — | WO | disclosed |