Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567251 | 0.91 | ADRB2 (0.49) | ADRB2ADRB3ADRB1 | |
| SCHEMBL14204727 | 0.90 | ADRB2 (0.46) | ADRB2ADRB3 | |
| SCHEMBL5041970 | 0.88 | ADRB2 (0.48) | ADRB2ADRB3 | |
| SCHEMBL5038655 | 0.88 | ADRB2 (0.46) | ADRB2ADRB3 | |
| SCHEMBL5038654 | 0.88 | ADRB2 (0.46) | ADRB2ADRB3 | |
| SCHEMBL5041964 | 0.88 | ADRB2 (0.48) | ADRB2ADRB3 | |
| SCHEMBL14204701 | 0.88 | ADRB2 (0.46) | ADRB2ADRB3 | |
| SCHEMBL14204723 | 0.85 | ADRB2 (0.56) | ADRB2ADRB3 | |
| SCHEMBL5037091 | 0.83 | ADRB2 (0.58) | ADRB2ADRB3 | |
| SCHEMBL6017532 | 0.83 | ADRB2 (0.58) | ADRB2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708992-B1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2007-08-08 | — | — | EP | disclosed |
| EP-1708992-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | Pfizer Limited (GB) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005080324-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |