Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MELK | Q14680 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567679 | 0.94 | MAPT (0.49) | SMN1; SMN2POLBTSHRMELKMAPT | |
| SCHEMBL8267125 | 0.81 | ABCB1 (0.46) | SMN1; SMN2POLBTSHRMAPTLMNA | |
| SCHEMBL5568182 | 0.79 | TP53 (0.43) | SMN1; SMN2POLBTSHRMAPTLMNA | |
| SCHEMBL5571870 | 0.79 | MAPT (0.44) | SMN1; SMN2POLBTSHRMAPTTDP1 | |
| SCHEMBL8267967 | 0.79 | NPC1 (0.51) | SMN1; SMN2POLBTSHRMAPTLMNA | |
| SCHEMBL5571848 | 0.78 | TP53 (0.47) | SMN1; SMN2POLBTSHRMAPTALDH1A1 | |
| SCHEMBL5571532 | 0.77 | MCHR1 (0.45) | SMN1; SMN2POLBTSHRMAPTTDP1 | |
| SCHEMBL5571850 | 0.76 | RAB9A (0.43) | SMN1; SMN2POLBTSHRMAPTLMNA | |
| SCHEMBL8266780 | 0.76 | RAB9A (0.47) | SMN1; SMN2POLBTSHRMAPTALDH1A1 | |
| SCHEMBL13725171 | 0.76 | MAPT (0.41) | SMN1; SMN2POLBTSHRMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |