Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573477 | 0.84 | SMN1; SMN2 (0.38) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL5571532 | 0.82 | MCHR1 (0.45) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL5571870 | 0.82 | MAPT (0.44) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL8267967 | 0.82 | NPC1 (0.51) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL5567679 | 0.81 | MAPT (0.49) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL5571848 | 0.81 | TP53 (0.47) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL8267125 | 0.79 | ABCB1 (0.46) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL13725171 | 0.79 | MAPT (0.41) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL8266780 | 0.78 | RAB9A (0.47) | RAB9APOLBTDP1TP53MAPK1 | |
| SCHEMBL5567288 | 0.76 | SMN1; SMN2 (0.51) | RAB9APOLBTDP1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |