Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL4954281 | 1.00 | TSHR (0.61) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL28125539 | 0.98 | TSHR (0.58) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL3930378 | 0.98 | TSHR (0.58) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL23159879 | 0.95 | USP2 (0.59) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL10406157 | 0.95 | TSHR (0.56) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL30304 | 0.95 | TSHR (0.56) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL8642766 | 0.93 | USP2 (0.62) | TSHRUSP2TDP1HTTMAPT | |
| Butoxyethanol SCHEMBL5926145 | 0.93 | TSHR (0.74) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL7873540 | 0.93 | TSHR (0.54) | TSHRUSP2TDP1HTTMAPT | |
| Propylene Glycol SCHEMBL8641201 | 0.93 | USP2 (0.62) | TSHRUSP2TDP1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 26319 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260147279-A1 | DEVELOPER COMPOSITION FOR METAL-CONTAINING PHOTORESIST, AND METHOD OF FORMING PATTERNS INCLUDING DEVELOPING METHOD USING THE COMPOSITION | SAMSUNG SDI CO., LTD. (KR) | 2026-05-28 | — | — | US | claimed |
| CN-118117169-B | Special additive for electrolyte, electrolyte and lithium ion battery | TIANMU LAKE INSTITUTE OF ADVANCED ENERGY STORAGE TECHNOLOGIES Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122095027-A | Modified maleated natural oil-based reaction products and slurry compositions containing the same | — | 2026-05-26 | — | — | CN | claimed |
| US-12637584-B2 | Waterborne polyurethane-epoxy resin based primer composition and its preparation method thereof | BASF COATINGS GMBH (DE) | 2026-05-26 | — | — | US | claimed |
| CN-122080904-A | Surfactant composition, nano emulsion, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080272-A | Precipitation-resistant high-density polyethylene with low ash content, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060355-A | Coating with covering and thermal-changing characteristics, thermosensitive color-developing material, preparation process and application | 山东世纪阳光纸业集团有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-118685108-B | Anti-dazzle antibacterial coating liquid and preparation method thereof, anti-dazzle antibacterial coating, anti-dazzle antibacterial optical film and polaroid and preparation method thereof | 宁波惠之星新材料科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-121610138-B | Fluorine-free silicon-containing anti-icing coating regulated and controlled based on organic tellurium compound and preparation method thereof | 西北工业大学 | 2026-05-19 | — | — | CN | claimed |
| EP-0489485-A1 | A process for welding plastics | TEXACO CHEMICAL COMPANY (US) | 1992-06-10 | — | — | EP | claimed |
| US-5069718-A | Potassium substituted inks for ink-jet printers | HEWLETT-PACKARD COMPANY (US) | 1991-12-03 | — | — | US | claimed |
| US-4786327-A | Dye preparation for thermal ink-jet printheads using ion exchange | HEWLETT-PACKARD COMPANY (US) | 1988-11-22 | — | — | US | claimed |
| CN-86100283-B | Method and device for extracting silver from film developing water | 中山大学 | 1987-09-09 | — | — | CN | claimed |
| CN-86100283-A | The extracting method and the device of silver in the cinefilm wash-down water | — | 1987-07-22 | — | — | CN | claimed |
| EP-0051161-B1 | ENCAPSULATION BY ENTRAPMENT WITHIN STARCH ADDUCT MATRIX | AGRO-CAP INTERNATIONAL, INC. (US) | 1985-03-27 | — | — | EP | claimed |
| US-4382813-A | Encapsulation by entrapment within starch adduct matrix | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1983-05-10 | — | — | US | claimed |
| US-4230609-A | INTERPOLYMER OF A HYDROPHOBIC MONOMER; AN ACRYLATE, VINYL ETHER, OR DIENE; AND HYDROPHILIC MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4124555-A | FILM FORMING | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| US-3971626-A | CITRATE AND ALCOHOL SOLVENT | HENKEL & CIE G.M.B.H. (DT) | 1976-07-27 | — | — | US | claimed |