Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654375 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL12652827 | 0.77 | KMT2A (0.52) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL14602583 | 0.73 | KDM4E (0.58) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL10465215 | 0.72 | MEN1 (0.65) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL15859393 | 0.71 | GRIN2D (0.49) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| Carbazole SCHEMBL27552113 | 0.71 | CTSV (0.67) | MEN1KMT2AKDM4EGLAHTT | |
| Hydrochloric Acid SCHEMBL2456350 | 0.71 | GRIN2D (0.50) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL2456353 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL14550190 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL17117303 | 0.68 | KMT2A (0.63) | MEN1KMT2AMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751154-A1 | 5-SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO[3,2-B] INDOL-2-ONES AND ANALOGS AS ANTI-VIRALS | Tibotec Pharmaceuticals Ltd. (IE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005111034-A1 | 5-SUBSTITUTED 1-PHENYL-1,5-DIHYDRO-PYRIDO’3,2-B! INDOL-2-ONES AND ANALOGS AS ANTI-VIRALS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |