SCHEMBL5568252

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL182533	0.89	PIK3CD (0.71)	PIK3CDPIK3CAPIK3CBPIK3CGKCNH2
	SCHEMBL5569427	0.86	KIT (0.58)	PIK3CDPIK3CAPIK3CBPIK3CGKCNH2
	SCHEMBL5568255	0.81	KIT (0.64)	KITEGFRERBB2KDRRAF1
	SCHEMBL6181412	0.79	EGFR (0.63)	PIK3CDPIK3CAPIK3CBPIK3CGKIT
	SCHEMBL4782102	0.79	WHR1 (0.61)	KITEGFRKDR
	SCHEMBL2126095	0.78	EGFR (0.61)	KITEGFRKDRRAF1MAPK14
	SCHEMBL2125179	0.78	EGFR (0.61)	KITEGFRERBB2KDRMET
	SCHEMBL29055018	0.78	ENPP1 (0.60)	PIK3CDPIK3CAPIK3CBPIK3CGKIT
	SCHEMBL30080208	0.78	ENPP1 (0.60)	PIK3CDPIK3CAPIK3CBPIK3CGKIT
	SCHEMBL5569012	0.78	EGFR (0.72)	EGFRERBB2AURKAAURKBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.