Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563898 | 1.00 | CTSK (0.34) | CTSKCTSSKMT2AMC4RDRD2 | |
| SCHEMBL7650981 | 0.88 | KDM4E (0.45) | CTSKKMT2ADRD2ALDH1A1KDM4E | |
| SCHEMBL7658235 | 0.86 | ACE (0.39) | CTSKCTSSKMT2AMC4RDRD2 | |
| SCHEMBL5567555 | 0.86 | ACE (0.39) | CTSKCTSSKMT2AMC4RDRD2 | |
| SCHEMBL7652246 | 0.86 | ACE (0.39) | CTSKCTSSKMT2AMC4RDRD2 | |
| SCHEMBL5567466 | 0.85 | MC4R (0.37) | CTSKCTSSKMT2AMC4RDRD2 | |
| SCHEMBL7653212 | 0.85 | MC4R (0.37) | CTSKCTSSKMT2AMC4RDRD2 | |
| SCHEMBL5563327 | 0.85 | CXCR3 (0.35) | CTSKCTSSKMT2AMC4RALDH1A1 | |
| SCHEMBL5563179 | 0.84 | KDM4E (0.37) | CTSKCTSSKMT2AALDH1A1KDM4E | |
| SCHEMBL7659015 | 0.82 | KDM4E (0.48) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-B1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-6335360-B1 | INDOLINE-2-CARBOXYLIC AMIDE DERIVATIVES; OBESITY, EATING AND PSYCHOLOGICAL DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-01 | — | — | US | disclosed |