SCHEMBL556848

SCHEMBL556848

C=CCN(CC=C)c1ccccc1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.37
CYP3A4 P08684 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
ALDH1A1 P00352 5/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 2/20 0.32
PTPN1 P18031 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28834703 0.93 C5AR1 (0.36) C5AR1CYP3A4SMN1; SMN2ALOX15CASP1
SCHEMBL9158117 0.82 ALDH1A1 (0.48) C5AR1CYP3A4ALDH1A1TSHRHSD17B10
SCHEMBL17714489 0.82 CYP1A2 (0.36) C5AR1ALDH1A1HSD17B10NPC1RAB9A
SCHEMBL9159932 0.80 JAK2 (0.35) CYP3A4ALDH1A1TSHRHSD17B10GAA
SCHEMBL2357793 0.79 ESR1 (0.36) C5AR1CYP3A4SMN1; SMN2ALOX15CASP1
SCHEMBL3631013 0.77 C5AR1 (0.38) C5AR1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL2221665 0.76 CASP1 (0.34) CYP3A4SMN1; SMN2CASP1CASP7ALDH1A1
SCHEMBL29499603 0.76 CASP1 (0.34) CYP3A4SMN1; SMN2CASP1CASP7ALDH1A1
SCHEMBL2786924 0.76 PRKCI (0.31) CASP1
SCHEMBL10352409 0.75 ALDH1A1 (0.40) C5AR1CYP3A4SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11034822-B2 Method for producing recycled thermoplastic rubber masterbatch with improved green strength and tack Tyrec Ltd. (IL) 2021-06-15 US claimed
US-20200181372-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2020-06-11 US claimed
EP-3630876-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2020-04-08 EP claimed
CN-110467764-A A kind of disposable plastic urine bag wear resistant resin material and preparation method thereof ANHUI NUOPUKANG MEDICAL EQUIPMENT CO LTD 2019-11-19 CN claimed
CN-109679733-A A kind of optical instrument lubricating grease and preparation method thereof 无锡飞天润滑油科技股份有限公司 2019-04-26 CN claimed
CN-107022125-B A kind of rubber composition and vulcanized rubber and its preparation method and application 中国石油化工股份有限公司 2019-03-26 CN claimed
WO-2018220618-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2018-12-06 WO claimed
CN-108655610-A A kind of mould proof scaling powder of water base washing-free antibacterial and preparation method thereof 苏州捷德瑞精密机械有限公司 2018-10-16 CN claimed
CN-108641794-A A kind of special main shaft seals grease of shield machine and preparation method and applications 中铁第五勘察设计院集团有限公司 2018-10-12 CN claimed
CN-108326471-A A kind of scaling powder additive 安徽宝辰机电设备科技有限公司 2018-07-27 CN claimed
CN-108077209-A A kind of repeatable durability utilized that cleans catches fly net mesh bag 太和县双飞绳业有限公司 2018-05-29 CN claimed
CN-107022125-A A kind of rubber composition is with vulcanizing rubber and its preparation method and application 中国石油化工股份有限公司 2017-08-08 CN claimed
CN-106543604-A A kind of acid and alkali-resistance tread-rubber and preparation method thereof 李尧 2017-03-29 CN claimed
CN-105131357-A Fatigue-resistant tread rubber and preparation method thereof SUZHOU GOODTIME TECHNOLOGY DEV CO LTD 2015-12-09 CN claimed
CN-103626665-B The synthetic method of a kind of N, N-dialkyl-pphenylenediamines JIANG University OF TECHNOLOGY (CN) 2015-07-29 CN claimed
CN-102936521-B Diesel oil composition and method for improving biodiesel oxidation stability CHINA PETROLEUM & CHEMICAL 2015-03-18 CN claimed
CN-101768484-B Diesel composition CHINA PETROLEUM & CHEMICAL 2015-02-25 CN claimed
CN-101899331-B Diesel composition and method for improving oxidation stability of biodiesel CHINA PETROLEUM & CHEMICAL 2015-01-14 CN claimed
JP-62062866-A None JP disclosed
US-3989732-A Photosensitive copper (I) complexes EASTMAN KODAK COMPANY (US) 1976-11-02 US disclosed