Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922345 | 0.79 | ALDH1A1 (0.33) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL1959317 | 0.75 | MEN1 (0.31) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL9829180 | 0.75 | CYP1A2 (0.40) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL9829183 | 0.75 | CYP1A2 (0.40) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL2163518 | 0.75 | CYP1A2 (0.40) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL3640223 | 0.75 | MEN1 (0.31) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL28418458 | 0.74 | TSHR (0.33) | ALDH1A1KIF11FFAR3TSHR | |
| Ammonia Solution, Strong SCHEMBL10585171 | 0.73 | MEN1 (0.30) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL11852978 | 0.73 | FFAR3 (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL20702119 | 0.73 | CPT2 (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458661-B1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE SRL (IT) | 2007-05-02 | — | — | EP | claimed |
| US-7067690-B2 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2006-06-27 | — | — | US | claimed |
| US-20050171379-A1 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-08-04 | — | — | US | claimed |
| EP-1458661-A1 | SEPARATION OF DIASTEREOISOMERS | Basell Poliolefine Italia S.p.A. (IT) | 2004-09-22 | — | — | EP | claimed |
| WO-2003055831-A1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-07-10 | — | — | WO | claimed |
| EP-1458661-B1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE SRL (IT) | 2007-05-02 | — | — | EP | disclosed |
| US-7067690-B2 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2006-06-27 | — | — | US | disclosed |
| US-20050171379-A1 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-08-04 | — | — | US | disclosed |
| EP-1458661-A1 | SEPARATION OF DIASTEREOISOMERS | Basell Poliolefine Italia S.p.A. (IT) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055831-A1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171379-A1 | Separation of diastereoisomers | SSB, C9, CA1 | MEN1 325/4885ALDH1A1 691/4885CYP1A2 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.