SCHEMBL3640223

SCHEMBL3640223

CCC(C)C(CC)(C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 2/20 0.31
USP2 O75604 1/20 0.31
KIF11 P52732 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10585171 0.98 MEN1 (0.30) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL27561061 0.89
SCHEMBL16045499 0.87
SCHEMBL13269578 0.82
SCHEMBL19514773 0.81 CHRM1 (0.41) ALDH1A1TSHR
SCHEMBL11122520 0.81 CA2 (0.31)
SCHEMBL28727587 0.79 CA2 (0.30)
SCHEMBL28727512 0.79 CA2 (0.30)
SCHEMBL2233286 0.79 ALDH1A1 (0.33) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL13269634 0.79 GRIK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018150-B1 PROCESS FOR THE PREPARATION OF SPHERICAL CATALYST PARTICLES INDIAN OIL CORP LTD (IN) 2020-03-11 EP claimed
EP-2966099-B1 PARTICLE SIZE DISTRIBUTION CONTROL THROUGH INTERNAL DONOR IN ZIEGLER-NATTA CATALYST INDIAN OIL CORP LTD (IN) 2020-03-11 EP claimed
EP-3053935-B1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME CHINA PETROLEUM & CHEM CORP (CN) 2019-05-08 EP claimed
EP-3162819-B1 IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF INDIAN OIL CORP LTD (IN) 2018-09-05 EP claimed
EP-2897985-B1 CATALYST FOR POLYMERIZATION OF OLEFINS AND PROCESS THEREOF INDIAN OIL CORP LTD (IN) 2017-03-08 EP claimed
CN-109666160-B Dynamic polymer with hybrid cross-linked network 厦门天策材料科技有限公司 2023-07-14 CN disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US disclosed
US-10357590-B2 Bioresorbable ceramic composition for forming a three dimensional scaffold DePuy Synthes Products, Inc. (US) 2019-07-23 US disclosed
US-10080750-B2 Aminopyrimidine derivatives for use as modulators of kinase activity MERCK PATENT GMBH (DE) 2018-09-25 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
WO-1998059108-A2 OXIDATION AND BLEACHING SYSTEM WITH ENZYMATICALLY PRODUCED OXIDIZING AGENTS BLUME, HILDEGARD (DE) 1998-12-30 WO disclosed
EP-0739907-A1 An olefin polymerization catalyst and a polyolefin production method TOKUYAMA CORPORATION (JP) 1996-10-30 EP disclosed
US-4470421-A SMOKING COMPOSITIONS CONTAINING A POLYMERIZABLE OR POLYMERIZED MALONATE FLAVOR ADDITIVE PHILIP MORRIS, INCORPORATED (US) 1984-09-11 US disclosed
US-4309544-A CONDENSATION OF 2-METHYLENE-QUINUCLIDIN-3-ONE WITH A KETONE OR AN THE PURDUE FREDERICK COMPANY (US) 1982-01-05 US disclosed
US-4262103-A SOLUTION POLYMERIZATION IN PRESENCE OF CATALYST MIXTURE OF ORGANOALUMINUM COMPOUND AND MOLYBDENUM SALT THE B. F. GOODRICH COMPANY (US) 1981-04-14 US disclosed
US-4226996-A 4-SUBSTITUTED-6-OXA-1-AZATRICYCLO/4.2.2.0.2.7/DODECAN-5-ONE SALT THE PURDUE FREDERICK COMPANY (US) 1980-10-07 US disclosed
US-4183938-A 1,8-Ethano-5-oxo-octa- and -decahydroquinolines and mydriatic compositions thereof THE PURDUE FREDERICK COMPANY (US) 1980-01-15 US disclosed
US-4083985-A 6-Oxa-1-aza tricyclo dodecan-5-ones as psychomotor stimulators THE PURDUE FREDERICK COMPANY (US) 1978-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A MEN1 1772/4885ALDH1A1 1103/4885CYP1A2 3113/4885
US-10080750-B2 Aminopyrimidine derivatives for use as modulators of kinase activity CDK6, TK1, MAP3K19 MEN1 3016/4885ALDH1A1 1612/4885CYP1A2 2852/4885
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 MEN1 1107/4885ALDH1A1 787/4885CYP1A2 2214/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 MEN1 2488/4885ALDH1A1 1061/4885CYP1A2 2465/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 MEN1 1056/4885ALDH1A1 1582/4885CYP1A2 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.