Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239417 | 0.82 | KDM4E (0.63) | KDM4ETOP2ANOS1NOS3ALDH1A1 | |
| SCHEMBL239416 | 0.82 | KDM4E (0.63) | KDM4ETOP2ANOS1NOS3ALDH1A1 | |
| SCHEMBL13754805 | 0.82 | KDM4E (0.63) | KDM4ETOP2ANOS1NOS3ALDH1A1 | |
| SCHEMBL5889037 | 0.77 | AGTR1 (0.59) | KDM4ETOP2AALDH1A1MAPTRAB9A | |
| SCHEMBL6150375 | 0.76 | AGTR1 (0.58) | KDM4ETOP2AALDH1A1MAPTRAB9A | |
| SCHEMBL3689607 | 0.74 | KDM4E (0.53) | KDM4ETOP2AALDH1A1MAPTRAB9A | |
| SCHEMBL3689609 | 0.74 | KDM4E (0.53) | KDM4ETOP2AALDH1A1MAPTRAB9A | |
| SCHEMBL13350386 | 0.74 | KDM4E (0.61) | KDM4ETOP2AALDH1A1MAPTRAB9A | |
| SCHEMBL25162057 | 0.71 | KDM4E (0.68) | KDM4ETOP2AALDH1A1MAPTRAB9A | |
| SCHEMBL31494657 | 0.71 | KDM4E (0.68) | KDM4ETOP2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753773-A1 | TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005118605-A1 | TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |