SCHEMBL239417

SCHEMBL239417

CC(=Nc1ccccc1)c1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.63
LMNA P02545 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
HTT P42858 2/20 0.53
TOP2A P11388 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
NAPRT Q6XQN6 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
MITF O75030 1/20 0.48
NOS3 P29474 2/20 0.47
NOS1 P29475 2/20 0.47
RAB9A P51151 4/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 2/20 0.46
ALOX12 P18054 1/20 0.46
GFER P55789 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239416 1.00 KDM4E (0.63) KDM4ELMNAALDH1A1MAPTHTT
SCHEMBL13754805 1.00 KDM4E (0.63) KDM4ELMNAALDH1A1MAPTHTT
SCHEMBL5889037 0.83 AGTR1 (0.59) KDM4ELMNAALDH1A1MAPTHTT
SCHEMBL20220197 0.83 KDM4E (0.53) KDM4ELMNAALDH1A1MAPTHTT
SCHEMBL6150375 0.82 AGTR1 (0.58) KDM4ELMNAALDH1A1MAPTHTT
SCHEMBL5569286 0.82 KDM4E (0.51) KDM4ELMNAALDH1A1MAPTHTT
Hydrochloric Acid SCHEMBL7179350 0.81 NOS1 (0.47) KDM4ELMNAALDH1A1MAPTHTT
Hydrochloric Acid SCHEMBL7171334 0.81 NOS1 (0.47) KDM4ELMNAALDH1A1MAPTHTT
Hydrochloric Acid SCHEMBL7182691 0.81 NOS1 (0.47) KDM4ELMNAALDH1A1MAPTHTT
Hydrochloric Acid SCHEMBL7176633 0.81 NOS1 (0.47) KDM4ELMNAALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 EP claimed
CN-1711275-A Palladium and platinum complexes COVION ORGANIC SEMICONDUCTORS (DE) 2005-12-21 CN claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 US disclosed
US-20260070936-A1 METAL COMPLEXES UDC IRELAND LTD (IE) 2026-03-12 US disclosed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 EP disclosed
US-12250871-B2 Metal complexes UDC IRELAND LIMITED (IE) 2025-03-11 US disclosed
CN-119504872-A Metal complex UDC爱尔兰有限公司 2025-02-25 CN disclosed
CN-114787173-B Metal complex UDC爱尔兰有限公司 2024-10-18 CN disclosed
CN-113646317-B Metal complex UDC爱尔兰有限公司 2024-10-18 CN disclosed
US-20240260448-A1 Metal Complexes UDC IRELAND LIMITED (IE) 2024-08-01 US disclosed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
WO-2010006666-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-01-21 WO disclosed
CN-100582114-C Aromatic monomer-and conjugated polymer-metal complexes SUMITOMO CHEMICAL CO 2010-01-20 CN disclosed
WO-2009146770-A2 ELECTRONIC DEVICE COMPRISING METAL COMPLEXES MERCK PATENT GMBH (DE) 2009-12-10 WO disclosed
CN-100549016-C Palladium and platinum complex MERCK PATENT GMBH (DE) 2009-10-14 CN disclosed
US-20080027220-A1 Metal Complexes MERCK PATENT GMBH (DE) 2008-01-31 US disclosed
CN-1997656-A Metal complexes MERCK PATENT GMBH (DE) 2007-07-11 CN disclosed
CN-1829725-A aromatic monomer and conjugated polymer-metal complex SUMITOMO CHEMICAL CO (JP) 2006-09-06 CN disclosed
CN-1711275-A Palladium and platinum complexes COVION ORGANIC SEMICONDUCTORS (DE) 2005-12-21 CN disclosed
US-20050031900-A1 Aromatic monomer-and conjugated polymer-metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070936-A1 METAL COMPLEXES SCO2, CBR1, CORO1C KDM4E 4498/4885LMNA 2021/4885ALDH1A1 2087/4885
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 KDM4E 3445/4885LMNA 556/4885ALDH1A1 2069/4885
US-12250871-B2 Metal complexes AP1M1, SOD1, AP3M1 KDM4E 3628/4885LMNA 4288/4885ALDH1A1 3790/4885
US-20080027220-A1 Metal Complexes AP1M1, SOD1, AP1G1 KDM4E 3323/4885LMNA 4651/4885ALDH1A1 363/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 KDM4E 4260/4885LMNA 547/4885ALDH1A1 1631/4885
US-20240260448-A1 Metal Complexes SOD1, AP1M1, AP3M1 KDM4E 3816/4885LMNA 4436/4885ALDH1A1 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.