Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247284 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6243667 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6242188 | 0.90 | ALDH1A1 (0.57) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL7043586 | 0.89 | KDM4E (0.56) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL7043599 | 0.89 | KDM4E (0.56) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6240391 | 0.87 | KDM4E (0.76) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6247072 | 0.87 | KDM4E (0.76) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL5569373 | 0.87 | KDM4E (0.76) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL7041574 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL5568469 | 0.86 | KDM4E (0.74) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-B1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-6335360-B1 | INDOLINE-2-CARBOXYLIC AMIDE DERIVATIVES; OBESITY, EATING AND PSYCHOLOGICAL DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-01 | — | — | US | disclosed |