Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243667 | 1.00 | ALDH1A1 (0.59) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL7043599 | 0.97 | KDM4E (0.56) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL7043586 | 0.97 | KDM4E (0.56) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6242188 | 0.92 | ALDH1A1 (0.57) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL5569424 | 0.91 | ALDH1A1 (0.72) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL7041574 | 0.90 | ALDH1A1 (0.55) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6245975 | 0.85 | ALDH1A1 (0.41) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7039233 | 0.82 | KDM4E (0.50) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7043163 | 0.82 | KDM4E (0.50) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7037763 | 0.80 | KDM4E (0.48) | ALDH1A1CYP2D6KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828851-B1 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INST NAT SANTE ETDE LA RECH ME (FR) | 2005-07-20 | — | — | EP | claimed |
| US-20030027743-A1 | Tripeptidylpeptidase inhibitors | INSERM | 2003-02-06 | — | — | US | claimed |
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | claimed |
| US-20030027743-A1 | Tripeptidylpeptidase inhibitors | INSERM | 2003-02-06 | — | — | US | disclosed |
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027743-A1 | Tripeptidylpeptidase inhibitors | DPP4, DPP3, DPP9 | ALDH1A1 630/4885CYP2D6 455/4885KDM4E 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.