SCHEMBL556956

SCHEMBL556956

CC(N)(O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
FABP5 Q01469 3/20 0.47
FABP7 O15540 2/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
EPHX2 P34913 1/20 0.45
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41
HTR2A P28223 1/20 0.41
CASP3 P42574 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809928 0.89 KMT2A (0.52) KMT2AFABP5FABP7CA1CA2
SCHEMBL10110895 0.86 KMT2A (0.51) KMT2AFABP5FABP7CA1CA2
SCHEMBL29456842 0.86 KMT2A (0.51) KMT2AFABP5FABP7CA1CA2
SCHEMBL28309128 0.85 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL14689743 0.85 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL15874638 0.85 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL15874406 0.85 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL18286329 0.85 KMT2A (0.46) KMT2AFABP5FABP7CA1CA2
SCHEMBL8453047 0.84 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL31517102 0.84 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124486-A1 GLP-1 RECEPTOR COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳信立泰药业股份有限公司 2025-06-19 WO disclosed
WO-2025098422-A1 MULTI-RECEPTOR CO-AGONIST COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 深圳信立泰药业股份有限公司 2025-05-15 WO disclosed
WO-2025092778-A1 GLP-1 COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳信立泰药业股份有限公司 2025-05-08 WO disclosed
CN-119912551-A Deuterated GLP-1 compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2025-05-02 CN disclosed
WO-2023129518-A1 TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES REGENERON PHARMACEUTICALS, INC. (US) 2023-07-06 WO disclosed
US-20150099808-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2015-04-09 US disclosed
US-8841257-B2 Inhibitors of STAT3 and uses thereof BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-09-23 US disclosed
US-20120035114-A1 INHIBITORS OF STAT3 AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-02-09 US disclosed
US-8030445-B2 Glycopeptide derivative THERAVANCE, INC. (US) 2011-10-04 US disclosed
CN-102186812-A Methods for preparing fluoroalkyl arylsulfinyl compounds and fluorinated compounds thereto UBE INDUSTRIES 2011-09-14 CN disclosed
US-6518242-B1 Derivatives of glycopeptide antibacterial agents THERAVANCE, INC. 2003-02-11 US disclosed
US-20030008812-A1 Glycopeptide derivatives THERAVANCE, INC. 2003-01-09 US disclosed
US-6455669-B1 GLYCOPROTEIN FOR USE IN THE TREATMENT AND PREVENTION OF BACTERIAL INFECTIONS THERAVANCE, INC. 2002-09-24 US disclosed
US-6444786-B1 BACTERICIDES ADVANCED MEDICINE, INC. 2002-09-03 US disclosed
US-6392012-B1 COMPOUND FOR USE IN TREATMENT AND PREVENTION OF BACTERIAL INFECTION ADVANCED MEDICINE, INC. 2002-05-21 US disclosed
EP-1140993-A1 GLYCOPEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Advanced Medicine, Inc. (US) 2001-10-10 EP disclosed
WO-2001057071-A2 GLYCOPEPTIDE DERIVATIVES HAVING ANTIBIOTIC ACTIVITY ADVANCED MEDICINE, INC. (US) 2001-08-09 WO disclosed
EP-1060189-A1 DERIVATIVES OF GLYCOPEPTIDE ANTIBACTERIAL AGENTS Advanced Medicine, Inc. (US) 2000-12-20 EP disclosed
WO-2000039156-A1 GLYCOPEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME ADVANCED MEDICINE, INC. (US) 2000-07-06 WO disclosed
WO-1999042476-A1 NOVEL ANTIBACTERIAL AGENTS ADVANCED MEDICINE, INC. (US) 1999-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008812-A1 Glycopeptide derivatives MGAT3, GYPA, GIPR KMT2A 4608/4885FABP5 2718/4885FABP7 3062/4885
US-20150099808-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS GLUL, ASNS, ARGLU1 KMT2A 1839/4885FABP5 1864/4885FABP7 505/4885
US-20120035114-A1 INHIBITORS OF STAT3 AND USES THEREOF STAT3, JAK2, STAT6 KMT2A 2506/4885FABP5 2080/4885FABP7 1427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.