Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568642 | 0.99 | S1PR1 (0.34) | S1PR1CNR1CNR2 | |
| SCHEMBL5570211 | 0.88 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL5565096 | 0.88 | S1PR1 (0.32) | S1PR1VDR | |
| SCHEMBL5569271 | 0.88 | S1PR1 (0.33) | S1PR1CNR1CNR2VDR | |
| SCHEMBL5569485 | 0.88 | CNR1 (0.32) | S1PR1CNR1CNR2 | |
| SCHEMBL5570033 | 0.84 | S1PR1 (0.34) | S1PR1CNR1CNR2VDR | |
| SCHEMBL5569795 | 0.84 | CNR1 (0.30) | CNR1CNR2 | |
| SCHEMBL5569463 | 0.83 | S1PR1 (0.35) | S1PR1CNR1CNR2VDR | |
| SCHEMBL5569491 | 0.83 | — | — | |
| SCHEMBL5565748 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312249-B2 | Vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-12-25 | — | — | US | claimed |
| US-20050182144-A1 | Novel vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-08-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182144-A1 | Novel vitamin D analogues | CYP24A1, CYP2R1, VDR | S1PR1 2544/4885CNR1 1270/4885CNR2 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.