Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359174 | 0.93 | THRB (0.40) | ALDH1A1THRBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL33745 | 0.93 | THRB (0.42) | ALDH1A1THRBSMN1; SMN2KDM4ETSHR | |
| SCHEMBL7256040 | 0.89 | THRB (0.44) | ALDH1A1THRBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL289015 | 0.89 | THRB (0.44) | ALDH1A1THRBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL33661 | 0.89 | THRB (0.44) | ALDH1A1THRBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL156151 | 0.89 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDTSHRMEN1 | |
| SCHEMBL522916 | 0.87 | EPHX2 (0.42) | ALDH1A1THRBSMN1; SMN2KDM4ETSHR | |
| SCHEMBL16196269 | 0.86 | THRB (0.38) | ALDH1A1THRBSMN1; SMN2KDM4ETSHR | |
| SCHEMBL1514966 | 0.85 | ALDH1A1 (0.44) | ALDH1A1THRBKDM4EHPGDTSHR | |
| SCHEMBL16291822 | 0.85 | EPHX2 (0.44) | ALDH1A1THRBSMN1; SMN2TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858965-A2 | POLYMER COMPOUND FOR BIOMEDICAL USE AND BIOCHIP SUBSTRATE USING SUCH A POLYMER COMPOUND | Sumitomo Bakelite Company, Limited (JP) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006101798-A2 | POLYMER COMPOUND FOR BIOMEDICAL USE AND BIOCHIP SUBSTRATE USING SUCH A POLYMER COMPOUND | SUMITOMO BAKELITE COMPANY LTD. (JP) | 2006-09-28 | — | — | WO | disclosed |