Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.74 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.74 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970784 | 0.83 | ALDH1A1 (0.64) | MEN1KMT2APOLBNPC1DUSP3 | |
| SCHEMBL4967530 | 0.82 | EGFR (0.56) | MEN1KMT2APOLBNPC1DUSP3 | |
| SCHEMBL27748217 | 0.81 | ABCG2 (0.72) | ABCG2EGFRALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL6786294 | 0.81 | ABCG2 (0.71) | ABCG2EGFRGAANCOA1NCOA3 | |
| SCHEMBL9017038 | 0.80 | EGFR (0.63) | MEN1KMT2APOLBNPC1ABCG2 | |
| SCHEMBL24429875 | 0.80 | WDR5 (0.67) | MEN1KMT2APOLBNPC1DUSP3 | |
| SCHEMBL29891034 | 0.80 | WDR5 (0.67) | MEN1KMT2APOLBNPC1DUSP3 | |
| SCHEMBL29116258 | 0.79 | ABCG2 (0.74) | MEN1KMT2APOLBNPC1DUSP3 | |
| SCHEMBL10106211 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2APOLBNPC1DUSP3 | |
| SCHEMBL4354577 | 0.79 | ABCG2 (1.00) | MEN1KMT2APOLBNPC1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | claimed |
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | disclosed |
| EP-1673346-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC Biotech AG (DE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040125-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC BIOTECH AG (DE) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | IRF3, PML, TPMT | MEN1 1784/4885KMT2A 1230/4885POLB 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.