Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.51 |
| ▸ | KARS1 | Q15046 | 7/20 | 0.48 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566772 | 0.91 | SYK (0.52) | SYKKARS1 | |
| SCHEMBL5570473 | 0.90 | SYK (0.49) | SYKKARS1MAP3K12 | |
| SCHEMBL2862479 | 0.89 | KARS1 (0.52) | SYKKARS1 | |
| Hydrochloric Acid SCHEMBL5570303 | 0.89 | HRH3 (0.41) | SYKKARS1MAP3K12 | |
| SCHEMBL2869964 | 0.88 | SYK (0.51) | SYKKARS1 | |
| SCHEMBL13136529 | 0.87 | SYK (0.52) | SYKKARS1MAP3K12 | |
| SCHEMBL2859023 | 0.87 | SYK (0.57) | SYKKARS1 | |
| Hydrochloric Acid SCHEMBL2868295 | 0.87 | SYK (0.51) | SYKKARS1 | |
| SCHEMBL2865592 | 0.87 | SYK (0.52) | SYKKARS1 | |
| SCHEMBL2861431 | 0.87 | KARS1 (0.55) | SYKKARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854793-A1 | NOVEL AMINOPYRIDINE COMPOUND WITH Syk INHIBITORY ACTIVITY | Japan Tobacco, Inc. (JP) | 2007-11-14 | — | — | EP | disclosed |